{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T11:06:28Z","timestamp":1760267188598,"version":"3.40.4"},"reference-count":16,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Cytologica"],"published-print":{"date-parts":[[2012]]},"abstract":"<b><i>Objective:<\/i><\/b> Autoimmune pancreatitis (AIP) is an inflammatory, IgG4-associated condition that often overlaps clinically and radiographically with pancreatic ductal adenocarcinoma. We reviewed our institutional experience with fine needle aspiration (FNA) cytology in patients subsequently diagnosed with AIP. <b><i>Study Design:<\/i><\/b> A retrospective review was conducted of FNA results correlating to all surgical pancreatic specimens diagnosed as AIP or lymphoplasmacytic sclerosing pancreatitis from 1984 to 2011. <b><i>Results:<\/i><\/b> AIP was diagnosed in 15 cases by surgical resection and in 2 by combined clinical findings and nondiagnostic biopsies. Of 20 aspirates from 17 patients, 1 was diagnosed as malignant, 1 as neoplasm (mucinous), 10 as atypical, 5 as benign, and 3 as scant or nondiagnostic. Of the 10 aspirates diagnosed as atypical, 1 was suspicious for malignancy, 1 could not exclude neuroendocrine neoplasm, 1 was markedly atypical, and 7 demonstrated scattered ductal atypia. Common morphologic features included hypocellularity, focal-to-marked ductal epithelial atypia, fibrous tissue fragments, and a smear background lacking red blood cells. <b><i>Conclusion:<\/i><\/b> On FNA, AIP most often leads to an \u2018atypical\u2019 cytopathologic interpretation and rarely may be diagnosed as adenocarcinoma. Thus, caution is warranted to avoid overdiagnosis on FNA when a mass lesion is reported in a patient with clinical or radiographic suspicion of AIP.<\/jats:p>","DOI":"10.1159\/000336135","type":"journal-article","created":{"date-parts":[[2012,4,25]],"date-time":"2012-04-25T10:40:58Z","timestamp":1335350458000},"page":"228-232","source":"Crossref","is-referenced-by-count":31,"title":["Fine Needle Aspirate of Autoimmune Pancreatitis (Lymphoplasmacytic Sclerosing Pancreatitis): Cytomorphologic Characteristics and Clinical Correlates"],"prefix":"10.1159","volume":"56","author":[{"given":"Brittany J.","family":"Holmes","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ralph H.","family":"Hruban","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher L.","family":"Wolfgang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Syed Z.","family":"Ali","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2012,4,26]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016%2F0046-8177%2891%2990087-6"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016%2FS0140-6736%2899%2900603-0"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1007%2Fs00535-007-2051-y"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1056%2FNEJM200103083441005"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1572-0241.2007.01264.x"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1038%2Fmodpathol.3800689"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1097%2F00000478-200301000-00012"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1007%2Fs00534-010-0321-1"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1148%2Frg.281065188"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1572-0241.2003.08727.x"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1097%2F01.pas.0000173656.49557.48"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1002%2Fcncr.11643"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1159%2F000326531"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1097%2FPAS.0b013e3182027717"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1097%2FBOR.0b013e3283412f4a"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1097%2FMPA.0b013e3182142fd2"}],"container-title":["Acta Cytologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/336135","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/336135","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T19:04:49Z","timestamp":1745435089000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000336135"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012]]},"references-count":16,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2012,6,1]]},"published-print":{"date-parts":[[2012,5,9]]}},"URL":"https:\/\/doi.org\/10.1159\/000336135","archive":["Portico"],"relation":{},"ISSN":["0001-5547","1938-2650"],"issn-type":[{"type":"print","value":"0001-5547"},{"type":"electronic","value":"1938-2650"}],"subject":[],"published":{"date-parts":[[2012]]}}}