{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T11:20:21Z","timestamp":1792149621111,"version":"4.4.0"},"reference-count":22,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Fetal Diagn Ther"],"published-print":{"date-parts":[[2012]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Objective:&lt;\/i&gt;&lt;\/b&gt; To report the incidence of fetal and maternal complications after selective fetoscopic laser surgery for twin-to-twin transfusion syndrome (TTTS). &lt;b&gt;&lt;i&gt;Methods:&lt;\/i&gt;&lt;\/b&gt; A total of 150 cases of TTTS were treated from January 2004 to June 2009 (period 1, 2004\u20132006, 62 cases; period 2, 2007 to June 2009, 88 cases). Fetal complications (double and single intrauterine fetal death, recurrence of TTTS, twin anemia-polycythemia sequence (TAPS), reversal of TTTS, cerebral lesions in one twin) and maternal complications were recorded, and retrospectively analyzed. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; Nineteen (12.6%), 58 (38.7%), 61 (40.7%) and 12 cases (8.0%) were classified preoperatively as Quintero stage I, II, III and IV, respectively. The anterior placenta was described in 73 cases (48.6%). Double and single fetal death occurred overall in 7.3 and 36.0% of cases, respectively. The rate of recurrence was 11.3%, of TAPS 3.3%, and of reversal of TTTS 1.3%. Cerebral lesions were diagnosed in 3 donors (2.0%). Eighteen cases (12.0%) of fetal complications had a second procedure (6 repeat laser, 4 serial amnioreduction, 8 bipolar cord coagulation). Pregnancies undergoing a second procedure delivered at a median gestational age of 30.2 weeks compared to 32.1 weeks for those not repeating (p = 0.04). Perinatal survival of at least one twin improved from 66.1 to 79.5% (p = 0.06) in the two consecutive periods. For every 10 laser surgeries performed, there was an average improvement of 1.5% in the predicted percentage of survival of at least one twin (OR 1.09, 95% CI 1.00\u20131.19). Major maternal complications occurred in 9 cases (6.0%), 3 of which required admission to intensive care unit. &lt;b&gt;&lt;i&gt;Conclusions:&lt;\/i&gt;&lt;\/b&gt; Fetal complications are common after fetoscopic laser surgery. In this experience, an increasing number of procedures improved the performance of a new fetoscopic laser center.<\/jats:p>","DOI":"10.1159\/000336227","type":"journal-article","created":{"date-parts":[[2012,3,23]],"date-time":"2012-03-23T18:57:58Z","timestamp":1332529078000},"page":"170-178","source":"Crossref","is-referenced-by-count":53,"title":["Fetal and Maternal Complications after Selective Fetoscopic Laser Surgery for Twin-to-Twin Transfusion Syndrome: A Single-Center Experience"],"prefix":"10.1159","volume":"31","author":[{"given":"M.A.","family":"Rustico","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.M.","family":"Lanna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Faiola","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"Schena","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Dell\u2019Avanzo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"Mantegazza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Parazzini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Lista","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Scelsa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Consonni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Ferrazzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2012,3,23]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1067%2FS0002-9378%2803%2900760-9"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1056%2FNEJMoa032597"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.ajog.2007.09.043"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.ajog.2005.08.069"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1159%2F000098715"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.siny.2007.07.005"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1159%2F000304512"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1159%2F000238108"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1471-0528.2010.02680.x"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1002%2Fpd.2548"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1515%2FJPM.2010.061"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1038%2Fsj.jp.7200292"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1056%2FNEJM200001063420102"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016%2F0002-9149%2892%2990300-N"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1007%2Fs00246-003-0591-3"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1469-0705.2000.00265.x"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.ajog.2005.09.013"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.ajog.2005.07.003"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016%2FS0301-2115%2800%2900437-1"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.ajog.2008.09.473"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1080%2F14767050701449638"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1471-0528.2007.01336.x"}],"container-title":["Fetal Diagnosis and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/336227","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/336227","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T19:05:17Z","timestamp":1745435117000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000336227"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012]]},"references-count":22,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2012,4,1]]},"published-print":{"date-parts":[[2012,4,26]]}},"URL":"https:\/\/doi.org\/10.1159\/000336227","archive":["Portico"],"relation":{},"ISSN":["1015-3837","1421-9964"],"issn-type":[{"value":"1015-3837","type":"print"},{"value":"1421-9964","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012]]}}}