{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T03:51:43Z","timestamp":1783482703920,"version":"3.55.0"},"reference-count":25,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatr Neurosurg"],"published-print":{"date-parts":[[2011]]},"abstract":"<b><i>Objective and Importance:<\/i><\/b> Gorham-Stout disease is a rare entity characterized by vascular proliferation causing local destruction of bone tissue. Owing to its low incidence and variable clinical presentation, the diagnosis requires a high degree of awareness by the clinician. <b><i>Clinical Presentation:<\/i><\/b> We present the case of a 2-year-old boy diagnosed of Gorham-Stout syndrome with involvement of the temporal bone and secondary cerebrospinal fluid (CSF) leakage. <b><i>Intervention:<\/i><\/b> Because of the CSF leakage, the patient required two surgical interventions. The second intervention included mastectomy and placement of a patch and a lumbar drainage device during 50 days, after which the leakage ceased. <b><i>Conclusion:<\/i><\/b> Gorham-Stout disease is a rare condition that can affect the skull base and even present with CSF leakage.<\/jats:p>","DOI":"10.1159\/000336877","type":"journal-article","created":{"date-parts":[[2012,3,23]],"date-time":"2012-03-23T18:57:58Z","timestamp":1332529078000},"page":"299-302","source":"Crossref","is-referenced-by-count":18,"title":["Gorham-Stout Disease and Cerebrospinal Fluid Otorrhea"],"prefix":"10.1159","volume":"47","author":[{"given":"Carmen","family":"Hern\u00e1ndez-Marqu\u00e9s","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana","family":"Serrano Gonz\u00e1lez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco","family":"Cordob\u00e9s Ortega","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javier","family":"Alvarez-Coca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Sirvent Cerda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando","family":"Carceller Lech\u00f3n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Azor\u00edn Cuadrillero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2012,3,23]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1056%2FNEJM183807110182305"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016%2F0002-9343%2854%2990027-3"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1007%2Fs00701-005-0806-x"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1157%2F13048084"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.tripleo.2008.02.028"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1196%2Fannals.1413.022"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1038%2Fncponc0660"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.bone.2009.11.015"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1002%2Fpath.989"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1210%2Fjc.81.5.1893"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1001%2Farchotol.129.12.1340"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.3121%2Fcmr.3.2.65"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1002%2Flary.20788"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016%2FS0033-8338%2806%2973127-7"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.crad.2006.04.014"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1097%2F01.mph.0000203721.83566.e6"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1097%2F00007632-198111000-00003"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.clon.2004.09.015"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016%2F0360-3016%2893%2990968-2"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1097%2F00043426-200310000-00016"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1016%2FS0140-6736%2805%2963639-2"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1002%2Fppul.20849"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.oraloncology.2005.04.007"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.ijporl.2009.12.007"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1007%2Fs00256-008-0525-5"}],"container-title":["Pediatric Neurosurgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/336877","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/336877","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T19:10:18Z","timestamp":1745435418000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000336877"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011]]},"references-count":25,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2012,5,1]]},"published-print":{"date-parts":[[2012,5,8]]}},"URL":"https:\/\/doi.org\/10.1159\/000336877","archive":["Portico"],"relation":{},"ISSN":["1016-2291","1423-0305"],"issn-type":[{"value":"1016-2291","type":"print"},{"value":"1423-0305","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011]]}}}