{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T06:27:42Z","timestamp":1769840862990,"version":"3.49.0"},"reference-count":19,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ophthalmologica"],"published-print":{"date-parts":[[2012]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Purpose:&lt;\/i&gt;&lt;\/b&gt; To evaluate short-term intraocular pressure (IOP) changes after phacoemulsification in glaucoma and normal patients and the effect of oral acetazolamide (Diamox) to control IOP in these patients. &lt;b&gt;&lt;i&gt;Methods:&lt;\/i&gt;&lt;\/b&gt; 120 patients undergoing cataract surgery were included in this prospective multicenter study involving 6 University Eye Clinics: 60 patients with well-controlled primary open-angle glaucoma (POAG) and 60 controls. Half of the study participants received oral acetazolamide, 250 mg, 1 and 6 h after surgery. The treated and untreated groups were matched for age and density of cataract. All patients underwent a standard phacoemulsification procedure and were checked for IOP with Goldmann tonometry in the morning before surgery and then at 3, 6, 21 and 24 h postoperatively by a masked evaluator. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; The group with POAG showed a significant postsurgical increase in IOP (p &lt; 0.001) at all time points. Six of thirty (20%) untreated POAG patients showed at least 1 IOP reading above 30 mm Hg whereas acetazolamide significantly reduced postoperative IOP at all time points (p &lt; 0.01) and in no case was IOP &gt;30 mm Hg. The control group had high IOP during the first 6 h (p &lt; 0.01), but normal values thereafter. &lt;b&gt;&lt;i&gt;Conclusion:&lt;\/i&gt;&lt;\/b&gt; A significant short-term IOP increase may be found after phacoemulsification both in POAG and normal patients; this is not dangerous in normal subjects, but can be potentially dangerous in POAG patients. The use of systemic acetazolamide provided significant control of IOP and could be considered a \u2018possible standard\u2019 management of cataract surgery in POAG patients.<\/jats:p>","DOI":"10.1159\/000337838","type":"journal-article","created":{"date-parts":[[2012,5,9]],"date-time":"2012-05-09T08:35:29Z","timestamp":1336552529000},"page":"154-158","source":"Crossref","is-referenced-by-count":19,"title":["Short-Term Changes in Intraocular Pressure after Phacoemulsification in Glaucoma Patients"],"prefix":"10.1159","volume":"228","author":[{"given":"Paolo","family":"Fogagnolo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco","family":"Centofanti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michele","family":"Figus","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paolo","family":"Frezzotti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Fea","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paolo","family":"Ligorio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Lembo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maurizio","family":"Digiuni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Umberto","family":"Lorenzi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luca","family":"Rossetti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2012,5,9]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1136%2Fbjo.2006.091447"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.jcrs.2004.06.046"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016%2FS0886-3350%2801%2900994-4"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.ophtha.2007.03.058"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.jcrs.2002.11.001"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1007%2Fs00417-005-1126-9"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.jcrs.2009.06.039"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1136%2Fbjo.85.2.139"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.ophtha.2005.05.011"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.jcrs.2008.12.030"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1186%2F1471-2415-5-24"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.jcrs.2007.06.046"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.jcrs.2003.12.050"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.jcrs.2004.07.024"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.jcrs.2003.08.029"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.3129%2FI08-130"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016%2FS0002-9394%2800%2900732-7"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1097%2F01.ijg.0000195932.48288.97"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1755-3768.1993.tb08598.x"}],"container-title":["Ophthalmologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/337838","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/337838","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T18:14:36Z","timestamp":1745432076000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000337838"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012]]},"references-count":19,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2012,9,1]]},"published-print":{"date-parts":[[2012,9,18]]}},"URL":"https:\/\/doi.org\/10.1159\/000337838","archive":["Portico"],"relation":{},"ISSN":["0030-3755","1423-0267"],"issn-type":[{"value":"0030-3755","type":"print"},{"value":"1423-0267","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012]]}}}