{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T11:06:29Z","timestamp":1760267189083,"version":"3.40.4"},"reference-count":8,"publisher":"S. Karger AG","issue":"5","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Med Princ Pract"],"published-print":{"date-parts":[[2012]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Objective:&lt;\/i&gt;&lt;\/b&gt; To report the first case of concomitant drug- and infection-induced antineutrophil cytoplasmic antibodies (ANCA)-associated vasculitis (AAV) in a patient treated with propylthiouracil (PTU) and suffering from tuberculosis. &lt;b&gt;&lt;i&gt;Presentation and Intervention:&lt;\/i&gt;&lt;\/b&gt; A 28-year-old woman with PTU-treated hyperthyroidism presented with fever, purpura, pulmonary cavitations and ANCA to myeloperoxidase, bactericidal\/permeability-increasing protein (BPI), proteinase-3 and elastase. Skin histopathology confirmed vasculitis. However, sputum examination revealed &lt;i&gt;Mycobacterium tuberculosis&lt;\/i&gt;. Remission was achieved after PTU withdrawal and treatment with antituberculosis drugs. &lt;b&gt;&lt;i&gt;Conclusion:&lt;\/i&gt;&lt;\/b&gt; Our case confirmed that BPI-ANCA are elevated in active tuberculosis. Multispecific ANCA were helpful for the diagnosis of concomitant PTU- and &lt;i&gt;M. tuberculosis&lt;\/i&gt;-induced AAV.<\/jats:p>","DOI":"10.1159\/000337944","type":"journal-article","created":{"date-parts":[[2012,4,25]],"date-time":"2012-04-25T10:41:55Z","timestamp":1335350515000},"page":"488-491","source":"Crossref","is-referenced-by-count":7,"title":["Concomitant Drug- and Infection-Induced Antineutrophil Cytoplasmic Autoantibody (ANCA)-Associated Vasculitis with Multispecific ANCA"],"prefix":"10.1159","volume":"21","author":[{"given":"Milica","family":"Kontic","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanja","family":"Radovanovic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Milos","family":"Nikolic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Branka","family":"Bonaci-Nikolic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2012,4,25]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1056%2FNEJM199711203372106"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1097%2FBOR.0b013e3283323538"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.ejim.2007.03.019"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.semarthrit.2006.03.003"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1097%2F00002281-200401000-00004"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1007%2Fs10067-010-1424-4"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1186%2Far1789"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1365-2249.2000.01228.x"}],"container-title":["Medical Principles and Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/337944","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/337944","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T18:15:27Z","timestamp":1745432127000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000337944"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012]]},"references-count":8,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2012,7,1]]},"published-print":{"date-parts":[[2012,7,31]]}},"URL":"https:\/\/doi.org\/10.1159\/000337944","archive":["Portico"],"relation":{},"ISSN":["1011-7571","1423-0151"],"issn-type":[{"type":"print","value":"1011-7571"},{"type":"electronic","value":"1423-0151"}],"subject":[],"published":{"date-parts":[[2012]]}}}