{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T10:27:36Z","timestamp":1771237656417,"version":"3.50.1"},"reference-count":11,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Urol Int"],"published-print":{"date-parts":[[2012]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Introduction:&lt;\/i&gt;&lt;\/b&gt; The use of ketamine as a recreational drug is on the increase among young adults attending clubs and parties. Recreational ketamine users have anecdotally reported increased lower urinary tract symptoms while using the substance. &lt;b&gt;&lt;i&gt;Methods:&lt;\/i&gt;&lt;\/b&gt; We describe the severe lower urinary tract symptoms experienced in 6 patients with chronic recreational ketamine use. We obtained a detailed history and physical examination along with further investigation to identify a relationship between recreational ketamine use and these symptoms. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; The urine cultures were sterile in all cases. Intravenous urography was performed in 3 patients and demonstrated bilateral upper ureteric narrow, mild bilateral hydronephrosis and contracted bladder urodynamic studies showed detrusor instability with urinary leakage when the bladder was filled to a capacity of 30\u2013 50 ml. Cystoscopy revealed a small capacity bladder with erythematous lesions throughout the bladder. Bladder biopsies were performed in 3 patients and showed up as chronic cystitis. Ketamine cessation along with intravesical sodium hyaluronate solution appeared to provide some symptomatic relief. &lt;b&gt;&lt;i&gt;Conclusion:&lt;\/i&gt;&lt;\/b&gt; Ketamine-associated urinary tract dysfunction appears to be a relatively new clinical phenomenon. The pathological mechanism of ketamine-associated urinary tract dysfunction is unknown and current management strategies are ketamine cessation along with intravesical sodium hyaluronate solution.<\/jats:p>","DOI":"10.1159\/000338098","type":"journal-article","created":{"date-parts":[[2012,6,18]],"date-time":"2012-06-18T15:31:11Z","timestamp":1340033471000},"page":"93-96","source":"Crossref","is-referenced-by-count":49,"title":["Ketamine-Associated Urinary Tract Dysfunction: An Underrecognized Clinical Entity"],"prefix":"10.1159","volume":"89","author":[{"given":"Yongqing","family":"Lai","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Song","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liangchao","family":"Ni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zebo","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xianxin","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shangqi","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yaoting","family":"Gui","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhichen","family":"Guan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhiming","family":"Cai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiongxian","family":"Ye","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2012,6,16]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016%2FS0376-8716%2802%2900243-0"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1159%2F000282244"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.urology.2007.01.038"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-2559.2009.03437.x"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1464-410X.2010.10031.x"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1742-1241.2010.02502.x"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1159%2F000282817"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1442-2042.2009.02361.x"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1038%2Fki.2009.139"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1464-410X.2008.07920.x"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.crad.2010.05.003"}],"container-title":["Urologia Internationalis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/338098","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/338098","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T18:16:20Z","timestamp":1745432180000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000338098"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012]]},"references-count":11,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2012,7,1]]},"published-print":{"date-parts":[[2012,7,25]]}},"URL":"https:\/\/doi.org\/10.1159\/000338098","archive":["Portico"],"relation":{},"ISSN":["0042-1138","1423-0399"],"issn-type":[{"value":"0042-1138","type":"print"},{"value":"1423-0399","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012]]}}}