{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T02:17:35Z","timestamp":1782181055995,"version":"3.54.5"},"reference-count":27,"publisher":"S. Karger AG","issue":"6","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Stereotact Funct Neurosurg"],"published-print":{"date-parts":[[2012]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Background:&lt;\/i&gt;&lt;\/b&gt; Deep brain stimulation (DBS) is a standard treatment for patients with disabling essential tremor. The short-term efficacy rate is well established. &lt;b&gt;&lt;i&gt;Objectives:&lt;\/i&gt;&lt;\/b&gt; To assess the long-term effects of DBS in our series and evaluate the durability of the effects over time. &lt;b&gt;&lt;i&gt;Methods:&lt;\/i&gt;&lt;\/b&gt; Eighty-four patients implanted with unilateral or bilateral DBS for essential tremor were asked to complete three mailed-in questionnaires to assess DBS efficacy objectively and subjectively. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; Twenty-six patients responded, with a median follow-up of 41 months. Approximately half of the patients had more than 48 months of follow-up. At the time of follow-up, the Tremor Rating Scale was reduced from a mean score of 7 (5\u20138) to 3 (2\u20133) with DBS OFF and ON, respectively. Quality of life, measured with a subset of items of the ADL Taxonomy, improved from a mean of 26 (23\u201333) to 12 (12\u201314), comparing DBS OFF and ON. No significant differences were seen when comparing efficacy at short- (&lt;12 months), middle- (12\u201348 months) or long-term (&gt;48 months) follow-ups. &lt;b&gt;&lt;i&gt;Conclusion:&lt;\/i&gt;&lt;\/b&gt; DBS has long-term efficacy for tremor control. This is associated with sustained benefits in quality of life. The duration of the follow-up was not associated with any significant difference in efficacy.<\/jats:p>","DOI":"10.1159\/000338683","type":"journal-article","created":{"date-parts":[[2012,9,27]],"date-time":"2012-09-27T16:19:09Z","timestamp":1348762749000},"page":"394-400","source":"Crossref","is-referenced-by-count":14,"title":["Long-Term Effects of Deep Brain Stimulation for Essential Tremor with Subjective and Objective Quantification via Mailed-In Questionnaires"],"prefix":"10.1159","volume":"90","author":[{"given":"Tatiana H.","family":"de Oliveira","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew R.","family":"Ginsberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott","family":"Cooper","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy","family":"Nowacki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Rezai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milind","family":"Deogaonkar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andre G.","family":"Machado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2012,9,27]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1212%2FWNL.54.1.8"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1002%2Fmds.870130105"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1159%2F000195691"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1097%2F00004691-200401000-00002"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016%2FS0090-3019%2897%2900459-X"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1002%2F1531-8257%28200101%2916%3A1%3C140%3A%3AAID-MDS1025%3E3.0.CO%3B2-T"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1212%2F01.WNL.0000096012.07360.1C"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.3171%2Fjns.2005.103.3.0400"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.3171%2Fjns.2006.104.4.506"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016%2F0140-6736%2891%2991175-T"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1080%2F02688690701552278"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1136%2Fjnnp.74.10.1387"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1002%2Fmds.1089"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.3171%2FJNS%2F2008%2F109%2F10%2F0640"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1600-0404.2008.01065.x"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.3109%2F11038129409106665"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1212%2FWNL.41.12.1982"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.3171%2Fjns.1996.84.2.0203"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1002%2Fmds.10309"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.nurt.2008.01.004"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.3171%2F2009.10.JNS09371"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1056%2FNEJM200002173420703"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1002%2Fmds.870130414"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1016%2FS0090-3019%2803%2900091-0"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1227%2F01.NEU.0000192692.95455.FD"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1002%2Fmds.22758"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1212%2FWNL.55.1.114"}],"container-title":["Stereotactic and Functional Neurosurgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/338683","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/338683","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T18:21:47Z","timestamp":1745432507000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000338683"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012]]},"references-count":27,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2012,12,1]]},"published-print":{"date-parts":[[2012,12,4]]}},"URL":"https:\/\/doi.org\/10.1159\/000338683","archive":["Portico"],"relation":{},"ISSN":["1011-6125","1423-0372"],"issn-type":[{"value":"1011-6125","type":"print"},{"value":"1423-0372","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012]]}}}