{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T13:29:28Z","timestamp":1783776568626,"version":"3.55.0"},"reference-count":8,"publisher":"S. Karger AG","issue":"6","license":[{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatr Neurosurg"],"published-print":{"date-parts":[[2011]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Background:&lt;\/i&gt;&lt;\/b&gt; Giant encephalocele is a rare condition and few published reports are available in the English literature. It is a challenge to neurosurgeons, even today. This series consists of 14 patients with giant encephaloceles treated at our institute. &lt;b&gt;&lt;i&gt;Material and Observation:&lt;\/i&gt;&lt;\/b&gt; Over a period of 8 years, from 2002 to 2009, 110 patients with encephaloceles were managed at our institute. Amongst them, 14 were children with giant encephaloceles. All patients had CT\/MRI or both prior to surgery, and all were operated upon. Four patients were neonates, under 1 month of age, and 9\/14 patients (64%) were under 3 months. The youngest child was a newborn baby aged 2 days. Except for 1 with an anterior encephalocele, the rest were patients with occipital encephaloceles. A CT scan was performed on 5 and an MRI on 1 patient. Both CT and MRI scans were performed on the other 8 patients. MRI\/CT showed hydrocephalus in 10\/14 patients. Of these, 7 required ventriculoperitoneal (VP) shunt, and the remaining 3 with mild to moderate hydrocephalus did not. Of the 7 patients who underwent VP shunt, 5 had a shunt during the encephalocele repair and 2 had a postoperative shunt for increasing hydrocephalus. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; Other associated anomalies recorded were acquired Chiari malformation in 3 patients, secondary craniostenosis with microcephaly in 5, and syringomyelia in 1 patient. All the patients underwent repair of encephalocele and 4 had suturectomy of coronal suture for the secondary craniostenosis. There were 2 postoperative deaths due to hypothermia. Among the 12 surviving patients, 9 had a good outcome and 3 had poor mental development. The present study shows overall good outcomes in 9\/14 (66%) patients.<\/jats:p>","DOI":"10.1159\/000338895","type":"journal-article","created":{"date-parts":[[2012,7,9]],"date-time":"2012-07-09T09:34:11Z","timestamp":1341826451000},"page":"406-411","source":"Crossref","is-referenced-by-count":33,"title":["Giant Encephalocele: A Study of 14 Patients"],"prefix":"10.1159","volume":"47","author":[{"given":"A.K.","family":"Mahapatra","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2012,7,7]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1007%2Fs00381-004-1020-5"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1054%2Fjocn.2001.1114"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.2176%2Fnmc.33.845"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1159%2F000048348"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1007%2Fs00381-006-0110-y"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1097%2F00008506-200304000-00012"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1007%2Fs00381-008-0721-6"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1212%2FWNL.54.5.1175"}],"container-title":["Pediatric Neurosurgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/338895","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/338895","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T18:23:23Z","timestamp":1745432603000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000338895"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011]]},"references-count":8,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2012,7,1]]},"published-print":{"date-parts":[[2012,7,25]]}},"URL":"https:\/\/doi.org\/10.1159\/000338895","archive":["Portico"],"relation":{},"ISSN":["1016-2291","1423-0305"],"issn-type":[{"value":"1016-2291","type":"print"},{"value":"1423-0305","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011]]}}}