{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:51:38Z","timestamp":1787017898621,"version":"build-2736575974"},"reference-count":27,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dermatology"],"published-print":{"date-parts":[[2012]]},"abstract":"<b><i>Background:<\/i><\/b> Few data are available concerning the efficiency of pulse corticosteroids in alopecia areata (AA).<b><i> Objective:<\/i><\/b> Our purpose was to assess the long-term outcomes of patients treated with methylprednisolone bolus. <b><i>Methods:<\/i><\/b> This study included 60 patients treated between 1995 and 2000. The short-term outcomes were analyzed in 2000. The long-term assessment of 30 patients was performed in 2010 by phone questionnaire. <b><i>Results:<\/i><\/b> Significant hair regrowth was observed in 10\/30 patients at 6 months after the bolus treatment. Half of the plurifocalis AA patients were responders at 6 months, but less than one quarter of alopecia totalis (AT) and alopecia universalis (AU) patients responded. Long-term outcomes were assessed after a mean duration of 12.3 years; 8\/10 initial responders had mild or no disease, and 14\/20 initial nonresponders had severe AA. <b><i>Conclusions:<\/i><\/b> This study confirmed the low efficiency, both short- and long-term, of this treatment for AT and AU.<\/jats:p>","DOI":"10.1159\/000341523","type":"journal-article","created":{"date-parts":[[2012,9,12]],"date-time":"2012-09-12T04:06:39Z","timestamp":1347422799000},"page":"81-87","source":"Crossref","is-referenced-by-count":29,"title":["Pulse Corticosteroid Therapy for Alopecia Areata: Long-Term Outcome after 10 Years"],"prefix":"10.1159","volume":"225","author":[{"given":"D.","family":"Staumont-Sall\u00e9","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Vonarx","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Lengrand","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Segard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Delaporte","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2012,9,10]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1001%2Fjama.1952.03680060018006"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1001%2Farchderm.1976.01630350025006"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.jaad.2006.05.008"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-2230.1994.tb01167.x"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1610-0387.2007.06608.x"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1159%2F000247268"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016%2FS0190-9622%2898%2970009-X"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1159%2F000246159"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1159%2F000051642"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1159%2F000107626"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016%2FS0190-9622%2896%2990323-0"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1159%2F000247540"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-2133.2008.08458.x"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1365-2133.2003.05535.x"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.sder.2008.12.002"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016%2FS0190-9622%2897%2970342-6"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1080%2F09546630701846095"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.jaad.2009.10.031"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.jaad.2005.09.010"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.annder.2010.06.031"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1468-3083.2006.01676.x"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-4632.2008.03743.x"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-2133.2011.10714.x"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.jaad.2005.09.025"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-4632.2004.02028.x"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1038%2Fjid.2010.232"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-2133.2008.09014.x"}],"container-title":["Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/341523","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/341523","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T14:39:14Z","timestamp":1745419154000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000341523"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012]]},"references-count":27,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2012,10,1]]},"published-print":{"date-parts":[[2012,10,11]]}},"URL":"https:\/\/doi.org\/10.1159\/000341523","archive":["Portico"],"relation":{"is-supplemented-by":[{"id-type":"doi","id":"10.6084\/m9.figshare.5123833","asserted-by":"subject"}]},"ISSN":["1018-8665","1421-9832"],"issn-type":[{"value":"1018-8665","type":"print"},{"value":"1421-9832","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012]]}}}