{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T11:53:38Z","timestamp":1785326018754,"version":"3.55.0"},"reference-count":11,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2012,11,3]],"date-time":"2012-11-03T00:00:00Z","timestamp":1351900800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2012,11,3]],"date-time":"2012-11-03T00:00:00Z","timestamp":1351900800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Fetal Diagn Ther"],"published-print":{"date-parts":[[2013]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Introduction:&lt;\/i&gt;&lt;\/b&gt; The embryogenesis of gastroschisis is not completely understood. The aim of our study was to evaluate the impact of a simple abdominal wall defect versus a defect including eviscerated intestine or omentum for the development of gastroschisis in a fetal lamb model. &lt;b&gt;&lt;i&gt;Material and Methods:&lt;\/i&gt;&lt;\/b&gt; At mid-gestation (day 77) an abdominal wall defect was fetoscopically created with three different approaches in 19 German blackhead sheep. The intestine was eviscerated in 7 fetuses (group 1). The peritoneum was incised and a patch of the omentum pulled through the incision in 5 fetuses (group 2). In 7 fetuses (group 3) the skin and rectus muscle were incised until the peritoneum was visible. In this group, no abdominal contents were exteriorized and the peritoneum was left intact. A second fetoscopic procedure was performed 21 days later, assessing the condition and extension of eviscerated bowel. The fetus was retrieved by Cesarean section on day 132 and evaluated. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; The second fetoscopy acting as a control for the creation of gastroschisis demonstrated eviscerated and inflamed intestine in all 3 groups. The amount of eviscerated intestine did not appear to depend on the size of the defect nor on its duration. &lt;b&gt;&lt;i&gt;Discussion:&lt;\/i&gt;&lt;\/b&gt; It appears that a simple incision of the abdominal wall with intact peritoneum is sufficient for the development of gastroschisis in a fetal sheep model. This finding may improve the understanding of the etiology of gastroschisis.<\/jats:p>","DOI":"10.1159\/000342421","type":"journal-article","created":{"date-parts":[[2012,11,5]],"date-time":"2012-11-05T08:02:59Z","timestamp":1352102579000},"page":"55-60","source":"Crossref","is-referenced-by-count":11,"title":["Abdominal Wall Incision with or without Exteriorization of Bowel: Results from a Fetal Lamb Model for the Embryogenesis of Gastroschisis"],"prefix":"10.1159","volume":"33","author":[{"given":"Robert","family":"Bergholz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Krebs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katharina","family":"Wenke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Boettcher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Andreas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bastian","family":"Tiemann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Birthe","family":"Jacobsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca","family":"Fahje","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carla","family":"Schmitz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beate","family":"Roth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Birgit","family":"Appl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Konrad","family":"Reinshagen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kurt","family":"Hecher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2012,11,3]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1053%2Fj.sempedsurg.2008.07.002"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016%2FS0022-3468%2880%2980130-8"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016%2FS0022-3476%2881%2980640-3"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1136%2Fadc.38.198.142"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1399-0004.2008.01142.x"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1007%2Fs00464-011-2048-8"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.jpedsurg.2010.04.017"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.2350%2F11-06-1053-CR.1"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1053%2Fjpsu.2001.28846"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.jpedsurg.2004.10.013"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016%2FS0022-3468%2899%2990162-8"}],"container-title":["Fetal Diagnosis and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/342421","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/342421","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T18:47:04Z","timestamp":1745434024000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000342421"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,11,3]]},"references-count":11,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2013,1,1]]},"published-print":{"date-parts":[[2013,1,15]]}},"URL":"https:\/\/doi.org\/10.1159\/000342421","archive":["Portico"],"relation":{},"ISSN":["1015-3837","1421-9964"],"issn-type":[{"value":"1015-3837","type":"print"},{"value":"1421-9964","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,11,3]]}}}