{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,7]],"date-time":"2025-10-07T11:34:16Z","timestamp":1759836856482,"version":"3.40.4"},"reference-count":14,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2012,12,6]],"date-time":"2012-12-06T00:00:00Z","timestamp":1354752000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2012,12,6]],"date-time":"2012-12-06T00:00:00Z","timestamp":1354752000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Cytologica"],"published-print":{"date-parts":[[2013]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Objective:&lt;\/i&gt;&lt;\/b&gt; Neuroendocrine carcinoma (NEC) of the uterine cervix is a highly aggressive type of tumor. Therefore, recognition of its cytology and histopathology is important for early diagnosis. &lt;b&gt;&lt;i&gt;Study Design:&lt;\/i&gt;&lt;\/b&gt; We report 6 cases of small-cell and 6 cases of large-cell NEC of the uterine cervix, including 5 cytology slides. AE1\/3, CEA, p63, p16, CD56, chromogranin and synaptophysin were detected. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; Two cytology slides of small-cell NEC showed sheet-like clusters. The tumor cells were uniformly small, with finely granular chromatin, scant cytoplasm and absent nucleoli. Three large-cell NEC smears showed palisading, molding and abortive rosettes with prominent eosinophilic nucleoli. The tumor cells had either abundant cytoplasm or no cytoplasm at all. The histopathology analysis indicated a transition from dysplasia glands or adenocarcinoma in situ glands to NEC in 6 cases. &lt;b&gt;&lt;i&gt;Conclusion:&lt;\/i&gt;&lt;\/b&gt; Cervical cytology of NEC has many unique characteristics, distinct from the characteristics of other lesions. We also demonstrated a hypothesis of the histogenesis of some NECs.<\/jats:p>","DOI":"10.1159\/000342516","type":"journal-article","created":{"date-parts":[[2012,12,6]],"date-time":"2012-12-06T14:40:07Z","timestamp":1354804807000},"page":"54-60","source":"Crossref","is-referenced-by-count":19,"title":["Twelve Cases of Neuroendocrine Carcinomas of the Uterine Cervix: Cytology, Histopathology and Discussion of Their Histogenesis"],"prefix":"10.1159","volume":"57","author":[{"given":"Shuxia","family":"Li","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huiting","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2012,12,6]]},"reference":[{"doi-asserted-by":"publisher","key":"ref1","DOI":"10.1053%2Fj.seminoncol.2006.10.028"},{"doi-asserted-by":"publisher","key":"ref2","DOI":"10.1016%2Fj.ygyno.2003.12.027"},{"doi-asserted-by":"publisher","key":"ref3","DOI":"10.1002%2Fdc.21834"},{"doi-asserted-by":"publisher","key":"ref4","DOI":"10.1007%2Fs00404-003-0482-0"},{"doi-asserted-by":"publisher","key":"ref5","DOI":"10.1097%2FPAS.0b013e3181758831"},{"doi-asserted-by":"publisher","key":"ref6","DOI":"10.1097%2Fpgp.0b013e31815698e7"},{"doi-asserted-by":"publisher","key":"ref7","DOI":"10.1007%2Fs004280000273"},{"doi-asserted-by":"publisher","key":"ref8","DOI":"10.1038%2Fmodpathol.3800148"},{"doi-asserted-by":"publisher","key":"ref9","DOI":"10.1006%2Fgyno.1999.5622"},{"doi-asserted-by":"publisher","key":"ref10","DOI":"10.1097%2F01.pas.0000213434.91868.b0"},{"doi-asserted-by":"publisher","key":"ref11","DOI":"10.1097%2F00004347-200107000-00016"},{"doi-asserted-by":"publisher","key":"ref12","DOI":"10.1097%2F00000478-199708000-00004"},{"doi-asserted-by":"publisher","key":"ref13","DOI":"10.1097%2FPAS.0b013e3181d1d457"},{"doi-asserted-by":"publisher","key":"ref14","DOI":"10.1097%2F01.PGP.0000071046.12278.D1"}],"container-title":["Acta Cytologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/342516","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/342516","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T18:48:25Z","timestamp":1745434105000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000342516"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,12,6]]},"references-count":14,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2013,2,1]]},"published-print":{"date-parts":[[2013,1,10]]}},"URL":"https:\/\/doi.org\/10.1159\/000342516","archive":["Portico"],"relation":{},"ISSN":["0001-5547","1938-2650"],"issn-type":[{"type":"print","value":"0001-5547"},{"type":"electronic","value":"1938-2650"}],"subject":[],"published":{"date-parts":[[2012,12,6]]}}}