{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T02:30:25Z","timestamp":1789871425326,"version":"4.0.1"},"reference-count":29,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Obes Facts"],"published-print":{"date-parts":[[2012]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Objective:&lt;\/i&gt;&lt;\/b&gt; To study a possible association between obstructive sleep apnea (OSA) severity, managed with noninvasive ventilation, and nonalcoholic steatohepatitis (NASH) in bariatric surgical patients. &lt;b&gt;&lt;i&gt;Methods&lt;\/i&gt;&lt;\/b&gt;: Medical records of 218 bariatric surgical patients who underwent liver biopsy were reviewed. OSA severity was determined from preoperative polysomnography (apnea-hypopnea index (AHI) \u2264 15 no\/mild OSA vs. AHI \u2265 16 moderate\/severe OSA). Patients diagnosed with OSA were prescribed noninvasive ventilation. Patients were categorized according to liver histopathology into 3 groups: i) no liver disease or simple steatosis, ii) mild NASH (steatosis with necroinflammation and mild fibrosis (stage 0\u20131)), and iii) advanced NASH (steatosis with necroinflammation and more advanced fibrosis (stage \u2265 2)). &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; 125 patients (57%) had no\/mild OSA, and 93 (43%) had moderate\/severe OSA. There was no difference in serum aminotransferases between patients by OSA severity classification. There was a high prevalence of hepatic histopathological abnormalities: 84% patients had steatosis, 57% had necroinflammation, 34% had fibrotic changes, and 14% had advanced NASH. There was no association between severity of NASH and severity of OSA. &lt;b&gt;&lt;i&gt;Conclusions:&lt;\/i&gt;&lt;\/b&gt; There is no association between stage of steatohepatitis and OSA severity among morbidly obese patients managed with noninvasive ventilation.<\/jats:p>","DOI":"10.1159\/000342677","type":"journal-article","created":{"date-parts":[[2012,9,17]],"date-time":"2012-09-17T07:08:29Z","timestamp":1347865709000},"page":"587-596","source":"Crossref","is-referenced-by-count":14,"title":["Nonalcoholic Steatohepatitis in Bariatric Patients with a Diagnosis of Obstructive Sleep Apnea"],"prefix":"10.1159","volume":"5","author":[{"given":"Toby N.","family":"Weingarten","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos B.","family":"Mantilla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James 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