{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T15:39:24Z","timestamp":1791041964972,"version":"4.1.0"},"reference-count":7,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ann Nutr Metab"],"published-print":{"date-parts":[[2012]]},"abstract":"<jats:p>The term \u2018scurvy\u2019 for the disease resulting from prolonged vitamin C deficiency had origins in \u2018scorbutus\u2019 (Latin), \u2018scorbut\u2019 (French), and \u2018Skorbut\u2019 (German). Scurvy was a common problem in the world\u2019s navies and is estimated to have affected 2 million sailors. In 1747, James Lind conducted a trial of six different treatments for 12 sailors with scurvy: only oranges and lemons were effective in treating scurvy. Scurvy also occurred on land, as many cases occurred with the \u2018great potato famine\u2019 in Ireland in 1845. Many animals, unlike humans, can synthesize their own vitamin C. Axel Holst and Theodor Fr\u00f6lich fortuitously produced scurvy in the guinea pig, which like humans requires vitamin C in the diet. In 1928, Albert Szent-Gy\u00f6rgyi isolated a substance from adrenal glands that he called \u2018hexuronic acid\u2019. Four years later, Charles Glen King isolated vitamin C in his laboratory and concluded that it was the same as \u2018hexuronic acid\u2019. Norman Haworth deduced the chemical structure of vitamin C in 1933.<\/jats:p>","DOI":"10.1159\/000343121","type":"journal-article","created":{"date-parts":[[2012,11,23]],"date-time":"2012-11-23T03:51:31Z","timestamp":1353642691000},"page":"259-264","source":"Crossref","is-referenced-by-count":98,"title":["The Discovery of Vitamin C"],"prefix":"10.1159","volume":"61","author":[{"given":"Kenneth J.","family":"Carpenter","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2012,11,26]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1097%2F00000441-184801000-00003"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1017%2FS0022172400033623"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1126%2Fscience.75.1944.357-a"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1038%2F129576a0"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1002%2Fhlca.193301601133"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1001%2Fjama.1967.03120110066009"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1097%2F00043764-197106000-00005"}],"container-title":["Annals of Nutrition and Metabolism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/343121","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/343121","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T14:21:42Z","timestamp":1745418102000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000343121"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012]]},"references-count":7,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2012,11,1]]},"published-print":{"date-parts":[[2012,11,26]]}},"URL":"https:\/\/doi.org\/10.1159\/000343121","archive":["Portico"],"relation":{},"ISSN":["0250-6807","1421-9697"],"issn-type":[{"value":"0250-6807","type":"print"},{"value":"1421-9697","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012]]}}}