{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T04:34:13Z","timestamp":1745469253414,"version":"3.40.4"},"reference-count":24,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dermatology"],"published-print":{"date-parts":[[2012]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Background:&lt;\/i&gt;&lt;\/b&gt; Psoriasis is a chronic, inflammatory skin disease associated with anxiety and depression. Infliximab (IFX) is a human\/mouse chimeric anti-TNF-\u03b1 antibody effective in the treatment of psoriasis. &lt;b&gt;&lt;i&gt;Objective:&lt;\/i&gt;&lt;\/b&gt; The aim of this study was to evaluate the prevalence of panic disorders in psoriatic patients during IFX infusions. &lt;b&gt;&lt;i&gt;Methods:&lt;\/i&gt;&lt;\/b&gt; A retrospective study was performed on patients affected with psoriasis who were treated with IFX from 2002 to 2011 at a single center. Panic disorders were defined using the clinical criteria of the Diagnostic and Statistical Manual of Mental Disorders, 4th edition. A population of dermatological patients under treatment with IVG, rituximab, apheresis, intravenous corticosteroids and antibiotics was considered as the control group. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; A total of 141 patients were evaluated. Of these, 6 (4.25%) experienced panic attacks during the infusion; 16 (11.3%) had a medical history of panic attack and of those 5\/16 (31%) experienced panic attacks during IFX infusion. In the control group panic attacks were not recorded. &lt;b&gt;&lt;i&gt;Conclusion:&lt;\/i&gt;&lt;\/b&gt; We describe 6 cases of patients in whom panic attacks were triggered by IFX infusion. Premedication with oral benzodiazepine and a slow rate of infusion is recommended.<\/jats:p>","DOI":"10.1159\/000343609","type":"journal-article","created":{"date-parts":[[2012,11,21]],"date-time":"2012-11-21T16:53:51Z","timestamp":1353516831000},"page":"236-241","source":"Crossref","is-referenced-by-count":4,"title":["Prevalence and Management of Panic Attacks during Infliximab Infusion in Psoriatic Patients"],"prefix":"10.1159","volume":"225","author":[{"given":"R.","family":"Saraceno","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Faleri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Ruzzetti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Centonze","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Chimenti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2012,11,22]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.2147%2FCCID.S3413"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1006%2Fcyto.1995.0029"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016%2FS0140-6736%2800%2904954-0"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1067%2Fmjd.2003.307"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016%2FS0140-6736%2805%2967566-6"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.jaad.2005.05.033"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-2133.2006.07316.x"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.3928%2F08910162-20100526-07"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1289%2Fehp.02110s4669"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1001%2Farchdermatol.2010.186"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1159%2F000090652"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016%2FS0016-5085%2803%2900701-7"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1136%2Fard.2004.024182"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1002%2F1529-0131%28200011%2943%3A11%3C2383%3A%3AAID-ANR2%3E3.0.CO%3B2-D"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1007%2Fs10620-006-8007-x"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016%2FS0002-9270%2800%2902159-6"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.crohns.2010.04.001"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016%2F0165-0327%2891%2990077-6"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1097%2F01.yct.0000154053.58022.10"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.bbi.2007.01.010"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.2174%2F187152410791196341"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1186%2Fgm161"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1001%2Farchpsyc.63.4.415"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1159%2F000316184"}],"container-title":["Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/343609","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/343609","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T18:26:42Z","timestamp":1745432802000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000343609"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012]]},"references-count":24,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2013,1,1]]},"published-print":{"date-parts":[[2013,1,22]]}},"URL":"https:\/\/doi.org\/10.1159\/000343609","archive":["Portico"],"relation":{},"ISSN":["1018-8665","1421-9832"],"issn-type":[{"type":"print","value":"1018-8665"},{"type":"electronic","value":"1421-9832"}],"subject":[],"published":{"date-parts":[[2012]]}}}