{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:51:39Z","timestamp":1787017899519,"version":"build-2736575974"},"reference-count":20,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dermatology"],"published-print":{"date-parts":[[2012]]},"abstract":"<b><i>Background:<\/i><\/b> Condylomata acuminata (CA) are caused by human papillomavirus. Most conventional therapies for CA have high recurrence rate. <b><i>Objectives:<\/i><\/b> To compare the recurrence rate of 5-aminolaevulinic acid photodynamic therapy (ALA-PDT) combined with CO<sub>2<\/sub> laser and CO<sub>2<\/sub> laser alone for CA treatment in mainland China. <b><i>Methods:<\/i><\/b> In this meta-analysis, 2,048 cases of CA from 22 articles were divided into two groups. The treatment group was treated by using ALA-PDT combined with CO<sub>2<\/sub> laser, and CO<sub>2<\/sub> laser alone was applied in the control group. The recurrence rate of the two groups was calculated and compared. <b><i>Results:<\/i><\/b> The recurrence rate was 42.67% (451\/1,057) in the control group and 10.29% (102\/991) in the treatment group, with a significant statistical difference between the two groups (&#x03C7;<sup>2<\/sup> = 271.98, p < 0.0001). <b><i>Conclusion:<\/i><\/b> ALA-PDT combined with CO<sub>2<\/sub> laser was more effective in decreasing the recurrence rate of CA compared with CO<sub>2<\/sub> laser alone. It might offer a wide clinical application for CA treatment.<\/jats:p>","DOI":"10.1159\/000346330","type":"journal-article","created":{"date-parts":[[2013,2,19]],"date-time":"2013-02-19T12:25:01Z","timestamp":1361276701000},"page":"364-370","source":"Crossref","is-referenced-by-count":23,"title":["Decrease Recurrence Rate of Condylomata Acuminata by Photodynamic Therapy Combined with CO<sub>2<\/sub> Laser in Mainland China: A Meta-Analysis"],"prefix":"10.1159","volume":"225","author":[{"given":"Xiaoling","family":"Zhu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongxiao","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Longfeng","family":"Cai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiming","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Limin","family":"Cai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2013,2,12]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1517\/14712598.2012.676036"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1099\/vir.0.039677-0"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.2910290205"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1258\/0956462041558168"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.5604\/17322693.987538"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1136\/sti.79.4.270"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0038583"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0037858"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1002\/9780470743386"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.315.7109.629"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-9740.2007.06352.x"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1590\/S0365-05962009000400009"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.clim.2010.02.020"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2006.07648.x"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.2174\/092986712799034932"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-1097.2011.01060.x"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2004.06189.x"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S29582"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2006.01902.x"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2010.10089.x"}],"container-title":["Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/346330","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/346330","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T14:45:16Z","timestamp":1745419516000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000346330"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012]]},"references-count":20,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2013,3,1]]},"published-print":{"date-parts":[[2013,3,7]]}},"URL":"https:\/\/doi.org\/10.1159\/000346330","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.717985319.793473461","asserted-by":"object"},{"id-type":"doi","id":"10.3410\/f.717985319.793473054","asserted-by":"object"}]},"ISSN":["1018-8665","1421-9832"],"issn-type":[{"value":"1018-8665","type":"print"},{"value":"1421-9832","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012]]}}}