{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T19:18:29Z","timestamp":1787771909606,"version":"build-2784847793"},"reference-count":32,"publisher":"S. Karger AG","issue":"6","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Chemotherapy"],"published-print":{"date-parts":[[2012]]},"abstract":"<b><i>Background:<\/i><\/b> Bacterial species from the ESKAPE group (i.e. <i>Enterococcus faecium<\/i>, <i>Staphylococcus aureus<\/i>, <i>Klebsiella pneumoniae<\/i>,<i> Acinetobacter baumannii<\/i>, <i>Pseudomonas aeruginosa<\/i> and <i>Enterobacter <\/i>species) are frequently resistant to antibiotics. The purpose of this study was to monitor the incidence of ESKAPE pathogens at the intensive care unit (ICU) of a tertiary care hospital in Monterrey, Mexico. <b><i>Methods:<\/i><\/b> All clinically relevant organisms isolated from June 2011 to June 2012 were included. Identification and susceptibility testing was performed using panels from Sensititre. Resistance to oxacillin, for <i>S. aureus,<\/i> and the production of extended spectrum \u03b2-lactamases (ESBLs), for <i>K. pneumonia,<\/i> were determined as defined by the Clinical Laboratory Standards Institute. Also, the presence of <i>vanA <\/i>and <i>vanB<\/i> genes was determined in <i>E. faecium <\/i>vancomycin (VAN)-resistant isolates. <b><i>Results:<\/i><\/b> The majority of pathogens (64.5%) isolated in the ICU unit were from the ESKAPE group. The organisms most frequently isolated were <i>A. baumannii <\/i>(15.8%) and <i>P. aeruginosa <\/i>(14.3%). A high resistance to carbapenems was detected for <i>A. baumannii<\/i> (75.3%) while 62% of <i>S. aureus<\/i> isolates were confirmed to be methicillin resistant. Of the <i>K. pneumoniae<\/i> isolates, 36.9% were ESBL producers. We detected three <i>E. faecium <\/i>VAN-resistant isolates, all of which contained the <i>vanA<\/i> gene. <b><i>Conclusion:<\/i><\/b> The presence of the ESKAPE group of pathogens is a major problem in the ICU setting. The results of this study support the implementation of special antimicrobial strategies to specifically target these microorganisms.<\/jats:p>","DOI":"10.1159\/000346352","type":"journal-article","created":{"date-parts":[[2013,3,21]],"date-time":"2013-03-21T09:44:48Z","timestamp":1363859088000},"page":"475-481","source":"Crossref","is-referenced-by-count":68,"title":["One-Year Surveillance of ESKAPE Pathogens in an Intensive Care Unit of Monterrey, Mexico"],"prefix":"10.1159","volume":"58","author":[{"given":"Jorge Mart\u00edn","family":"Llaca-D\u00edaz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soraya","family":"Mendoza-Olazar\u00e1n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adrian","family":"Camacho-Ortiz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samantha","family":"Flores","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elvira","family":"Garza-Gonz\u00e1lez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2013,3,21]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2008.06.016"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1159\/000339488"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1159\/000224657"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1186\/cc9997"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1086\/533452"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1086\/655995"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1186\/cc6820"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1159\/000321018"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00058-07"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.diagmicrobio.2004.02.003"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1159\/000319903"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.18.4.657-686.2005"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjp.0707632"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/174.3.529"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1001\/jama.298.15.1763"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01157-10"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.diagmicrobio.2006.12.022"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.37.11.2311"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1159\/000086574"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1002\/iub.533"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1086\/518842"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1086\/320183"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1159\/000220245"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1016\/S0924-8579(99)00131-4"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.48.12.4574-4581.2004"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01509-06"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1159\/000339483"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.022970-0"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2003.00698.x"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2009.04.006"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2010.03226.x"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.3201\/eid1305.061421"}],"container-title":["Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/346352","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/346352","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/346352","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T14:45:36Z","timestamp":1745419536000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000346352"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012]]},"references-count":32,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2013,4,1]]},"published-print":{"date-parts":[[2013,4,16]]}},"URL":"https:\/\/doi.org\/10.1159\/000346352","archive":["Portico"],"relation":{},"ISSN":["0009-3157","1421-9794"],"issn-type":[{"value":"0009-3157","type":"print"},{"value":"1421-9794","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012]]}}}