{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T13:47:50Z","timestamp":1783086470581,"version":"3.54.6"},"reference-count":40,"publisher":"S. Karger AG","issue":"4-5","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"},{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Kidney Blood Press Res"],"published-print":{"date-parts":[[2013]]},"abstract":"<b><i>Background: <\/i><\/b>Secondary hyperparathyroidism is associated with vascular calcification and arterial stiffness in patients with end-stage renal disease. The aim of this study was to analyze the frequency of intradialytic hypotension (IDH) and cardiovascular function before and after parathyroidectomy (PTX) in maintenance hemodialysis patients. <b><i>Methods: <\/i><\/b>We compared predialytic and intradialytic blood pressure, left and right ventricular ejection fraction (LVEF and RVEF), and cardiothoracic ratio 1 month before PTX, and 6 and 12 months after PTX. IDH was defined as a decrease in systolic blood pressure \u2265 20 mmHg or a decrease in mean arterial pressure \u2265 10 mmHg. <b><i>Results: <\/i><\/b>At the time of PTX, the mean age of the patients was 57.4 \u00b1 12.0 years, and the mean dialysis vintage was 12.2 \u00b1 5.8 years. At baseline, 6 months, and 12 months after PTX, the average numbers of sessions disturbed by IDH during 13 dialysis sessions (1 month) were 6.4, 3.9 (<i>p<\/i> < 0.016 <i>vs. <\/i>baseline), and 4.0 sessions (<i>p<\/i> < 0.037 <i>vs. <\/i>baseline, <i>p<\/i> = 0.801 <i>vs. <\/i>6 months), respectively. LVEF and RVEF were improved significantly after PTX. Furthermore, volume status was also improved, as evidenced by the significantly greater ultrafiltration volume and reduced cardiothoracic ratio. <b><i>Conclusions: <\/i><\/b>Hemodialysis patients with severe secondary hyperparathyroidism are more likely to achieve normotensive and euvolemic status after PTX, probably through improved heart function and reduced IDH episodes.<\/jats:p>","DOI":"10.1159\/000350160","type":"journal-article","created":{"date-parts":[[2013,9,26]],"date-time":"2013-09-26T14:05:43Z","timestamp":1380204343000},"page":"323-331","source":"Crossref","is-referenced-by-count":14,"title":["Parathyroidectomy Reduces Intradialytic Hypotension in Hemodialysis Patients with Secondary 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