{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T13:50:21Z","timestamp":1779889821813,"version":"3.53.1"},"reference-count":16,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neonatology"],"published-print":{"date-parts":[[2013]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Background:&lt;\/i&gt;&lt;\/b&gt; Serotonin reuptake inhibitor (SRI) medications are commonly in use during pregnancy. &lt;b&gt;&lt;i&gt;Objectives:&lt;\/i&gt;&lt;\/b&gt; To evaluate short-term neonatal clinical signs among infants exposed to intrauterine SRI medications, in order to estimate the need for postnatal monitoring and observation. &lt;b&gt;&lt;i&gt;Methods:&lt;\/i&gt;&lt;\/b&gt; Retrospective review of clinical data in medical files of term infants born to mothers who reported treatment with SRIs during pregnancy. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; Out of 401 infants in the study group, 165 (41%) were reported to have at least 1 clinical symptom, including respiratory distress, jitteriness, restlessness, feeding difficulties, regurgitations, fever \u226538\u00b0C, a short cyanotic event and convulsions. In the symptomatic group, 70% exhibited mild symptoms, among them restlessness, jitteriness or feeding difficulties, while around 30% exhibited significant symptoms. Overall, 12% of the total cohort, mostly males (70%), presented significant clinical symptoms, but none had an urgent or life-threatening condition. Infants in the study group were shorter in length and had a higher rate of Apgar score &lt;7 at 1 min, meconium-stained amniotic fluid and respiratory distress. &lt;b&gt;&lt;i&gt;Conclusions:&lt;\/i&gt;&lt;\/b&gt; Despite the high incidence of clinical signs among infants born to SRI-treated mothers, most of their symptoms were mild and self-limited. These infants should be observed while they are close to their mothers on the maternity ward for 48 h after birth.<\/jats:p>","DOI":"10.1159\/000350506","type":"journal-article","created":{"date-parts":[[2013,5,24]],"date-time":"2013-05-24T08:01:54Z","timestamp":1369382514000},"page":"65-70","source":"Crossref","is-referenced-by-count":15,"title":["Short-Term Neonatal Outcome among Term Infants after in utero Exposure to Serotonin Reuptake Inhibitors"],"prefix":"10.1159","volume":"104","author":[{"given":"Leah","family":"Leibovitch","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noa","family":"Rymer-Haskel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irit","family":"Schushan-Eisen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacob","family":"Kuint","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tzipora","family":"Strauss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayala","family":"Maayan-Metzger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2013,5,24]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1001\/archpedi.158.4.312"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2012.02.009"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1001\/jama.279.8.609"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199610033351402"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.63.8.898"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1001\/archpediatrics.2009.164"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1001\/archpedi.160.2.173"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1542\/peds.113.2.368"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1001\/jama.293.19.2372"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1080\/14767050802255488"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1007\/s002280050357"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc060602"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.167.12.1246"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.earlhumdev.2011.08.005"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.psyneuen.2011.11.011"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa052744"}],"container-title":["Neonatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/350506","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/350506","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T18:18:20Z","timestamp":1745432300000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000350506"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013]]},"references-count":16,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2013,7,1]]},"published-print":{"date-parts":[[2013,7,5]]}},"URL":"https:\/\/doi.org\/10.1159\/000350506","archive":["Portico"],"relation":{},"ISSN":["1661-7800","1661-7819"],"issn-type":[{"value":"1661-7800","type":"print"},{"value":"1661-7819","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013]]}}}