{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T02:46:15Z","timestamp":1789872375193,"version":"4.0.1"},"reference-count":14,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ophthalmologica"],"published-print":{"date-parts":[[2013]]},"abstract":"<b><i>Purpose:<\/i><\/b> The purpose of our study was to assess the macular thickness and the electrophysiological changes in keratoconic patients without any systemic or ocular disorders.<b><i> Methods: <\/i><\/b>64 eyes of 32 keratoconus patients as well as 60 eyes of 30 controls participated in the study. All participants underwent a complete ophthalmological examination, including best-corrected visual acuity (BCVA) assessment, color vision testing, fundus examination, intraocular pressure measurement, central foveal thickness (CFT) measurement by optical coherence tomography (OCT) scan, and multifocal-electroretinogram (mf-ERG) recording. CFT, retinal response density (RRD) and P<sub>1<\/sub> latency were measured. <b><i>Results:<\/i><\/b> There was no statistically significant difference between the two groups concerning CFT and P<sub>1<\/sub> latency in mf-ERG. The RRD in mf-ERG differed significantly between keratoconus patients and controls. Of note, BCVA was positively associated with RRD in keratoconus patients. <b><i>Conclusion:<\/i><\/b> In some cases of keratoconus, a macular dysfunction not visible ophthalmoscopically may coexist and the low visual acuity could be due not only to the corneal abnormality, but also to the photoreceptor dysfunction. As a result, the preoperative electrophysiological study of patients with keratoconus is crucial to avoid a needless corneal transplantation.<\/jats:p>","DOI":"10.1159\/000350801","type":"journal-article","created":{"date-parts":[[2013,5,7]],"date-time":"2013-05-07T09:04:44Z","timestamp":1367917484000},"page":"203-207","source":"Crossref","is-referenced-by-count":26,"title":["Assessment of the Macula in Keratoconus: An Optical Coherence Tomography and Multifocal Electroretinography Study"],"prefix":"10.1159","volume":"229","author":[{"given":"Marilita M.","family":"Moschos","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irini P.","family":"Chatziralli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chryssanthi","family":"Koutsandrea","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georgia","family":"Siasou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dimitrios","family":"Droutsas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2013,4,26]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/S0039-6257(97)00119-7"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2003.06.020"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.clae.2007.03.001"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1038\/sj.eye.6702692"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2007.03.021"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1002\/1096-8628(20000828)93:5<403::AID-AJMG11>3.0.CO;2-A"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/S0886-3350(00)00556-3"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1994.01090220118033"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1989.01070020581044"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0b013e3181e16dd0"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(00)00371-8"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1038\/sj.eye.6701318"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1046\/j.1475-1313.2003.00097.x"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1076\/ceyr.28.1.63.23494"}],"container-title":["Ophthalmologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/350801","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/350801","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T18:21:09Z","timestamp":1745432469000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000350801"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013]]},"references-count":14,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2013,5,1]]},"published-print":{"date-parts":[[2013,5,24]]}},"URL":"https:\/\/doi.org\/10.1159\/000350801","archive":["Portico"],"relation":{},"ISSN":["0030-3755","1423-0267"],"issn-type":[{"value":"0030-3755","type":"print"},{"value":"1423-0267","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013]]}}}