{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T15:28:52Z","timestamp":1777562932348,"version":"3.51.4"},"reference-count":6,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2013,11,7]],"date-time":"2013-11-07T00:00:00Z","timestamp":1383782400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"},{"start":{"date-parts":[[2013,11,7]],"date-time":"2013-11-07T00:00:00Z","timestamp":1383782400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Rep Dermatol"],"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Importance:&lt;\/i&gt;&lt;\/b&gt; Golimumab is a human monoclonal antibody, used for rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis. Adverse reactions are increasing with this class of medication (tumor necrosis factor \u03b1 inhibitors). &lt;b&gt;&lt;i&gt;Observations:&lt;\/i&gt;&lt;\/b&gt; The authors present a case of a female patient who presented with psoriasis pustulosa after the use of golimumab for rheumatoid arthritis. &lt;b&gt;&lt;i&gt;Conclusions and Relevance:&lt;\/i&gt;&lt;\/b&gt; Paradoxically, in this case, golimumab, which is used for psoriasis, induced the pustular form of this disease. We are observing an increasing number of patients who develop collateral effects with tumor necrosis factor \u03b1 inhibitors, and the understanding of the mechanism of action and how these adverse reactions occur may contribute to avoid these sometimes severe situations.<\/jats:p>","DOI":"10.1159\/000350930","type":"journal-article","created":{"date-parts":[[2013,11,7]],"date-time":"2013-11-07T07:42:55Z","timestamp":1383810175000},"page":"326-331","source":"Crossref","is-referenced-by-count":7,"title":["Paradoxical Reaction to Golimumab: Tumor Necrosis Factor \u03b1 Inhibitor Inducing Psoriasis Pustulosa"],"prefix":"10.1159","volume":"5","author":[{"given":"Marien Siqueira Soto","family":"Lopes","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beatriz Moritz","family":"Trope","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Paula Rua Rochedo","family":"Rodriguez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rachel Lima","family":"Grynszpan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tullia","family":"Cuzzi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcia","family":"Ramos-e-Silva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2013,11,7]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.143.2.223"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1080\/15569520500536568"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharmthera.2007.10.001"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.2165\/00128071-200708030-00002"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1002\/art.23835"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20050500"}],"container-title":["Case Reports in Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/350930","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/350930","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T18:22:24Z","timestamp":1745432544000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000350930"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,11,7]]},"references-count":6,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2013,12,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000350930","archive":["Portico"],"relation":{},"ISSN":["1662-6567"],"issn-type":[{"value":"1662-6567","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,11,7]]}}}