{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T10:03:57Z","timestamp":1770717837401,"version":"3.49.0"},"reference-count":30,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dig Surg"],"published-print":{"date-parts":[[2013]]},"abstract":"<b><i>Background:<\/i><\/b> Long-term functional results of ileal pouch-anal anastomosis (IPAA) with mucosal proctectomy (MP) for ulcerative colitis (UC) are satisfactory but may be compromised by perianal fistulae. <b><i>Methods:<\/i><\/b> We analyzed the effect of the level of MP (above or below the dentate line) on the risk of perianal fistulae in 151 patients undergoing IPAA for UC. <b><i>Results:<\/i><\/b> A postoperative perianal fistula occurred in 12 patients (10 with MP from the level above the dentate line and 2 below). Patients developing perianal fistulae after IPAA were significantly younger at IPAA (23 vs. 32 years, p = 0.015). Age <25 years at UC onset (hazard ratio, HR, 3.5, p<i> = <\/i>0.041), age <30 years at IPAA (HR 4.3, p = 0.015) and MP above the dentate line (HR 4.7, p = 0.010) were significant risk factors for perianal fistulae after IPAA. Multivariate analysis showed that age <30 years at IPAA (HR 4.4, p = 0.018) and MP above the dentate line (HR 6.0, p = 0.012) were significant risk factors. <b><i>Conclusion:<\/i><\/b> IPAA with MP below the dentate line for UC might reduce the risk of postoperative perianal fistulae.<\/jats:p>","DOI":"10.1159\/000351443","type":"journal-article","created":{"date-parts":[[2013,7,8]],"date-time":"2013-07-08T07:02:06Z","timestamp":1373266926000},"page":"219-224","source":"Crossref","is-referenced-by-count":9,"title":["Full Mucosal Proctectomy Initiated below the Dentate Line May Prevent the Development of a Perianal Fistula after Ileal Pouch-Anal Anastomosis for Ulcerative Colitis"],"prefix":"10.1159","volume":"30","author":[{"given":"Toshimitsu","family":"Araki","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshiki","family":"Okita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroyuki","family":"Fujikawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuhiro","family":"Inoue","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuhiko","family":"Mohri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masato","family":"Kusunoki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2013,7,6]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1136%2Fbmj.2.6130.85"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1007%2FBF02987076"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1007%2FBF02055426"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1136%2Fbmj.1.5224.463"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.0007-1323.2001.01983.x"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1002%2Fbjs.1800800750"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1007%2FBF02234229"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1097%2F01.sla.0000152018.99541.f1"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1007%2FDCR.0b013e31819a5c52"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1463-1318.2007.01211.x"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1002%2Fbjs.1800751016"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.3748%2Fwjg.15.769"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1002%2Fbjs.1800780415"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1097%2F00000658-199706000-00004"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1097%2F01.sla.0000225031.15405.a3"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1365-2168.1997.02684.x"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1365-2168.1998.00689.x"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1097%2F00000658-199508000-00003"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1007%2FDCR.0b013e31819eef8f"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1002%2Fbjs.1800760732"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1002%2Fbjs.5071"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1097%2FSLA.0b013e31814539b1"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1159%2F000085356"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1007%2FBF02237428"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1016%2FS0002-9610%2897%2989634-1"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1463-1318.2004.00606.x"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1007%2FBF02552595"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1007%2Fs002689900394"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1007%2FBF02049932"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1463-1318.2009.02014.x"}],"container-title":["Digestive Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/351443","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/351443","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T18:26:57Z","timestamp":1745432817000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000351443"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013]]},"references-count":30,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2013,8,1]]},"published-print":{"date-parts":[[2013,8,20]]}},"URL":"https:\/\/doi.org\/10.1159\/000351443","archive":["Portico"],"relation":{},"ISSN":["0253-4886","1421-9883"],"issn-type":[{"value":"0253-4886","type":"print"},{"value":"1421-9883","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013]]}}}