{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T08:12:30Z","timestamp":1780733550069,"version":"3.54.1"},"reference-count":23,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dermatology"],"published-print":{"date-parts":[[2013]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Background:&lt;\/i&gt;&lt;\/b&gt; Psoriatic nail disease is increasingly recognised to be of major clinical and research relevance. Clinical assessment remains the current gold standard for its evaluation. &lt;b&gt;&lt;i&gt;Objective:&lt;\/i&gt;&lt;\/b&gt; We compared optical coherence tomography (OCT) and ultrasound (US) for nail disease assessment in psoriatic disease. &lt;b&gt;&lt;i&gt;Methods:&lt;\/i&gt;&lt;\/b&gt; 18 patients with at least one involved nail and 12 healthy controls were scanned using OCT; psoriatic patients also had an US scan (using a linear probe at 9-14 MHz). Nail and contour abnormalities were documented. Clinical onychopathy was scored independently using the modified Nail Psoriasis Severity Index. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; Among 180 nails, 67.8% had clinical findings whereas 33.9% were abnormal by US and 44.4% had abnormalities on OCT. A positive OCT had a sensitivity and specificity of 44.4 and 95.8%, respectively, with a positive likelihood ratio of 10.7 for nail disease. OCT demonstrated 76.3% absolute agreement compared with clinical assessment and 65% with US. OCT detected subtle abnormalities in 12 clinically normal nails and in 41 nails with normal US findings. &lt;b&gt;&lt;i&gt;Conclusion:&lt;\/i&gt;&lt;\/b&gt; These findings show that OCT has a potential for the systematic characterisation of psoriatic nail changes and could be useful in diagnosis and more objective assessment of treatment response.<\/jats:p>","DOI":"10.1159\/000351702","type":"journal-article","created":{"date-parts":[[2013,8,23]],"date-time":"2013-08-23T07:04:30Z","timestamp":1377241470000},"page":"45-51","source":"Crossref","is-referenced-by-count":43,"title":["Potential Use of Optical Coherence Tomography and High-Frequency Ultrasound for the Assessment of Nail Disease in Psoriasis and Psoriatic Arthritis"],"prefix":"10.1159","volume":"227","author":[{"given":"Sibel Z.","family":"Aydin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Concepci\u00f3n","family":"Castillo-Gallego","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zoe R.","family":"Ash","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppina","family":"Abignano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helena","family":"Marzo-Ortega","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miriam","family":"Wittmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Del Galdo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dennis","family":"McGonagle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2013,8,24]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1159\/000246274"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1067\/S0190-9622(03)00910-1"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1002\/art.24172"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2005.07.073"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2012-201617"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1002\/1529-0131(199906)42:6<1080::AID-ANR2>3.0.CO;2-7"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(97)12004-9"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/kel214"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2011-200478"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1159\/000343607"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1159\/000332974"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1159\/000335571"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1002\/art.21736"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0846.2001.007001060.x"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-010-1623-z"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1159\/000329434"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2007.08118.x"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1159\/000333000"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0846.2012.00626.x"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2011.10461.x"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2011.10730.x"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0507.2009.01717.x"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0507.2012.02198.x"}],"container-title":["Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/351702","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/351702","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T18:29:29Z","timestamp":1745432969000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000351702"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013]]},"references-count":23,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2013,10,1]]},"published-print":{"date-parts":[[2013,10,3]]}},"URL":"https:\/\/doi.org\/10.1159\/000351702","archive":["Portico"],"relation":{},"ISSN":["1018-8665","1421-9832"],"issn-type":[{"value":"1018-8665","type":"print"},{"value":"1421-9832","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013]]}}}