{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T00:53:03Z","timestamp":1768783983609,"version":"3.49.0"},"reference-count":32,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiology"],"published-print":{"date-parts":[[2013]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Objectives:&lt;\/i&gt;&lt;\/b&gt; Our study aims to determine the role of serum adiponectin in chronic heart failure (CHF) and cardiac cachexia (CC). &lt;b&gt;&lt;i&gt;Methods:&lt;\/i&gt;&lt;\/b&gt; Ninety consecutive patients were included in the study. Patients were divided into three groups: 30 CHF patients with CC, 30 CHF patients without CC, and 30 healthy individuals. Adiponectin levels were measured through human ELISA kits. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; Levels of serum adiponectin were significantly higher in the CHF patients with cachexia in comparison with the other groups (CHF with CC: 58.4 \u00b1 15.5 ng\/ml vs. CHF without CC: 24 \u00b1 6.7 ng\/ml and controls: 7.7 \u00b1 3.4 ng\/ml; p = 0.001). Serum adiponectin was negatively correlated with BMI, high-sensitivity C-reactive protein, and hemoglobin (r = -0.37, p = 0.02; r = -0.29, p = 0.02; r = -0.18, p = 0.03, respectively) in the CHF patients with cachexia. Additionally, serum adiponectin levels were positively correlated with B-type natriuretic protein levels, left ventricle end-diastolic and end-systolic diameters (r = 0.36, p = 0.02; r = 0.46, p = 0.01; r = 0.49, p = 0.006, respectively) in the CHF patients with cachexia. &lt;b&gt;&lt;i&gt;Conclusion:&lt;\/i&gt;&lt;\/b&gt; Our findings suggest that adiponectin may play a critical role in the pathogenesis of cardiac remodeling and anemia in CC.<\/jats:p>","DOI":"10.1159\/000353291","type":"journal-article","created":{"date-parts":[[2013,9,18]],"date-time":"2013-09-18T06:56:49Z","timestamp":1379487409000},"page":"207-213","source":"Crossref","is-referenced-by-count":6,"title":["Serum Adiponectin, Anemia and Left Ventricular Dimensions in Patients with Cardiac Cachexia"],"prefix":"10.1159","volume":"126","author":[{"given":"Evin","family":"Bozcali","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Veli","family":"Polat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Handan","family":"Akbulut","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mustafa","family":"Ferzeyn Yavuzkir","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ilgin","family":"Karaca","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2013,9,18]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1053\/euhj.1999.1882"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(96)07015-8"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1006\/bbrc.1996.0587"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1038\/nm1557"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000042707.50032.19"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2006.06.053"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.2337\/diabetes.54.2.534"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehm033"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1093\/eurjhf\/hfp046"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2007.12.002"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.104.530972"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2005.083345"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehi204"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2005.10.005"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1253\/circj.CJ-11-1549"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1253\/circj.71.623"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1053\/euhj.1999.1746"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000054164.99881.00"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1096\/fj.14.10.1345"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2009.02.038"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2009.12.015"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1006\/bbrc.1999.0255"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1161\/01.ATV.20.6.1595"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2009.976"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1507\/endocrj.EJ12-0320"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000055188.83694.B3"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1093\/eurjhf\/hfr044"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2009.07.042"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1016\/j.trsl.2009.07.005"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-05-1033"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1038\/nm1137"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/cvn310"}],"container-title":["Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/353291","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/353291","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/353291","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T18:34:45Z","timestamp":1745433285000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000353291"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013]]},"references-count":32,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2013,11,1]]},"published-print":{"date-parts":[[2013,11,18]]}},"URL":"https:\/\/doi.org\/10.1159\/000353291","archive":["Portico"],"relation":{},"ISSN":["0008-6312","1421-9751"],"issn-type":[{"value":"0008-6312","type":"print"},{"value":"1421-9751","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013]]}}}