{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T04:34:41Z","timestamp":1745469281526,"version":"3.40.4"},"reference-count":29,"publisher":"S. Karger AG","issue":"5-6","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur Neurol"],"published-print":{"date-parts":[[2013]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Background and Purpose:&lt;\/i&gt;&lt;\/b&gt; Craniocervical artery stenosis is an important etiology for transient ischemic attack (TIA). We hypothesized ABCD and ABCD2 scores can predict craniocervical artery stenosis in patients with TIA. &lt;b&gt;&lt;i&gt;Methods:&lt;\/i&gt;&lt;\/b&gt; ABCD and ABCD2 scores were calculated in a total of 479 consecutive first-ever TIA patients in Nanjing Stroke Registry Program and compared with angiographic imaging derived from MRI or invasive catheter-based angiography. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; Overall craniocervical artery (O-CA) stenosis was found in 197 (41.1%) patients. Extracranial craniocervical artery (E-CA) and intracranial craniocervical artery (I-CA) stenosis was found in 101 (21.1%) and 110 (23%) cases, respectively. ABCD and ABCD2 scores with similar accuracy for O-CA (AUC&lt;sub&gt;ABCD&lt;\/sub&gt; 0.71, AUC&lt;sub&gt;ABCD2&lt;\/sub&gt; 0.70), E-CA (AUC&lt;sub&gt;ABCD&lt;\/sub&gt; 0.72, AUC&lt;sub&gt;ABCD2&lt;\/sub&gt; 0.72) and I-CA stenosis (AUC&lt;sub&gt;ABCD&lt;\/sub&gt; 0.62, AUC&lt;sub&gt;ABCD2&lt;\/sub&gt; 0.62) were both independent predictors for various categories of artery stenosis after being adjusted for non-ABCD2 parameters. The cut-off points were equally 4 in both predicting rules. For ABCD, sensitivity was 57.4, 65.3 and 52.7% and specificity 77.0, 70.4 and 67.5% for O-CA\/E-CA\/I-CA, respectively. For ABCD2, sensitivity was 61.9, 69.3 and 58.2% and specificity 72.3, 65.6 and 63.1%. &lt;b&gt;&lt;i&gt;Conclusions:&lt;\/i&gt;&lt;\/b&gt; In patients with TIA, despite an association between ABCD and ABCD2 scores and underlying craniocervical artery stenosis, the clinical utility was limited by unsatisfactory sensitivity and specificity.<\/jats:p>","DOI":"10.1159\/000353299","type":"journal-article","created":{"date-parts":[[2013,10,22]],"date-time":"2013-10-22T06:41:05Z","timestamp":1382424065000},"page":"333-339","source":"Crossref","is-referenced-by-count":2,"title":["Correlation between ABCD, ABCD2 Scores and Craniocervical Artery Stenosis in Patients with Transient Ischemic 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