{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T14:43:04Z","timestamp":1745505784147,"version":"3.40.4"},"reference-count":11,"publisher":"S. Karger AG","issue":"2","license":[{"start":{"date-parts":[[2013,6,20]],"date-time":"2013-06-20T00:00:00Z","timestamp":1371686400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"},{"start":{"date-parts":[[2013,6,20]],"date-time":"2013-06-20T00:00:00Z","timestamp":1371686400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Rep Dermatol"],"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Introduction:&lt;\/i&gt;&lt;\/b&gt; Polyacrylamide hydrogel has been considered a safe and biocompatible soft tissue filler, and it has been widely used in cosmetic procedures. However, recent studies have revealed some complications with polyacrylamide filler injections. &lt;b&gt;&lt;i&gt;Case Report:&lt;\/i&gt;&lt;\/b&gt; We present the case of foreign-body granulomas of the glabella, which subsequently formed an infectious ulcer 3 years after a polyacrylamide injection. An immunohistochemical evaluation of the foreign-body granulomas was performed in order to study the relationship between foreign-body granulomas and immune response. &lt;b&gt;&lt;i&gt;Conclusion:&lt;\/i&gt;&lt;\/b&gt; We believe that our analysis of foreign-body granulomas 1 and 3 years after a filler injection may contribute to revealing the mechanism of chronic and intractable infections after filler injections.<\/jats:p>","DOI":"10.1159\/000353346","type":"journal-article","created":{"date-parts":[[2013,6,24]],"date-time":"2013-06-24T07:40:45Z","timestamp":1372059645000},"page":"181-185","source":"Crossref","is-referenced-by-count":4,"title":["A Case of Foreign-Body Granuloma of the Glabella due to Polyacrylamide Filler and an Intractable Ulcer after Skin Biopsy: An Immunohistochemical Evaluation of Inflammatory Changes"],"prefix":"10.1159","volume":"5","author":[{"given":"Kio","family":"Park","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fuyuko","family":"Nishiwaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenji","family":"Kabashima","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshiki","family":"Miyachi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2013,6,20]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1007\/s00266-009-9359-3"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1001\/archfaci.6.3.204"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1007\/s00266-010-9617-4"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1007\/s00266-011-9660-9"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.a.32218"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1007\/s10227-002-2102-1"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e3181ead122"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2009.09.021"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1097\/01.prs.0000293758.61624.68"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2009.01338.x"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2009.06.036"}],"container-title":["Case Reports in Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/353346","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/353346","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T18:35:38Z","timestamp":1745433338000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000353346"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,6,20]]},"references-count":11,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2013,8,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000353346","archive":["Portico"],"relation":{},"ISSN":["1662-6567"],"issn-type":[{"type":"electronic","value":"1662-6567"}],"subject":[],"published":{"date-parts":[[2013,6,20]]}}}