{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T04:35:00Z","timestamp":1745469300978,"version":"3.40.4"},"reference-count":25,"publisher":"S. Karger AG","issue":"4-6","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dig Surg"],"published-print":{"date-parts":[[2013]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Aims:&lt;\/i&gt;&lt;\/b&gt; The purpose of this study was to assess the feasibility of laparoscopic intersphincteric resection (LAP-ISR) for rectal cancer in terms of morbidity, oncological outcomes, and functional results. &lt;b&gt;&lt;i&gt;Methods:&lt;\/i&gt;&lt;\/b&gt; Thirty-seven patients with primary low rectal cancer cT1-T2 underwent LAP-ISR. Surgical outcomes, pathological results, postoperative complications, oncological outcomes, and functional results were analyzed retrospectively. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; Three patients (8.1%) had carcinoma in situ, 22 (59.5%) had pT1 tumor, and 11 (29.7%) had pT2 tumor. Eleven patients (29.7%) were diagnosed as being node positive, while 26 (70.3%) had node-negative disease. The median operative time was 315 min (range: 195-502). The median blood loss was 37 ml (range: 0-745). One case was converted to open surgery. Pathological complete resection was achieved in all cases. There was no surgical mortality. Postoperative complications of grade III-IV on the Clavien-Dindo classification were observed in 16.2% of the patients. The median follow-up period was 2.8 years (range: 187-2,241 days), and 3-year disease-free survival was 93.1%. No patient developed local recurrence. The functional result was objectively good. &lt;b&gt;&lt;i&gt;Conclusion: &lt;\/i&gt;&lt;\/b&gt;LAP-ISR can be recommended as a feasible, ultimate sphincter-preserving procedure with acceptable functional and intermediate-term oncological outcomes in patients with cT1-T2 very low rectal cancer.<\/jats:p>","DOI":"10.1159\/000354034","type":"journal-article","created":{"date-parts":[[2013,8,20]],"date-time":"2013-08-20T07:11:06Z","timestamp":1376982666000},"page":"272-277","source":"Crossref","is-referenced-by-count":14,"title":["Feasibility of Laparoscopic Intersphincteric Resection for Patients with cT1-T2 Low Rectal Cancer"],"prefix":"10.1159","volume":"30","author":[{"given":"Akio","family":"Shiomi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yusuke","family":"Kinugasa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomohiro","family":"Yamaguchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Syunsuke","family":"Tsukamoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroyuki","family":"Tomioka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroyasu","family":"Kagawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2013,8,20]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800810944"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02238569"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800691019"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e318236c448"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-1318.2010.02528.x"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.5540"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1007\/DCR.0b013e318202388f"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1097\/01.sla.0000133083.54934.ae"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800651008"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1097\/01.sla.0000154551.06768.e1"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1007\/BF02238568"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1007\/s10350-003-0088-4"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1007\/DCR.0b013e31819739a0"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1001\/jama.287.3.321"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(02)09290-5"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)66545-2"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1007\/s11605-009-1150-x"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-011-1277-2"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(86)92612-7"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-012-1846-z"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1007\/s10350-006-0598-y"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1007\/DCR.0b013e31819f5fa2"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1007\/s10350-005-0134-5"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19831001)52:7<1317::AID-CNCR2820520731>3.0.CO;2-6"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-008-0047-3"}],"container-title":["Digestive Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/354034","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/354034","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T18:41:13Z","timestamp":1745433673000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000354034"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013]]},"references-count":25,"journal-issue":{"issue":"4-6","published-online":{"date-parts":[[2014,3,1]]},"published-print":{"date-parts":[[2014,3,3]]}},"URL":"https:\/\/doi.org\/10.1159\/000354034","archive":["Portico"],"relation":{},"ISSN":["0253-4886","1421-9883"],"issn-type":[{"type":"print","value":"0253-4886"},{"type":"electronic","value":"1421-9883"}],"subject":[],"published":{"date-parts":[[2013]]}}}