{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T22:30:11Z","timestamp":1792189811565,"version":"4.4.0"},"reference-count":18,"publisher":"S. Karger AG","issue":"2","license":[{"start":{"date-parts":[[2013,11,5]],"date-time":"2013-11-05T00:00:00Z","timestamp":1383609600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2013,11,5]],"date-time":"2013-11-05T00:00:00Z","timestamp":1383609600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Respiration"],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Background:&lt;\/i&gt;&lt;\/b&gt; Positive airway pressure (PAP) therapy is the standard treatment for obstructive sleep apnea syndrome (OSAS). &lt;b&gt;&lt;i&gt;Objectives:&lt;\/i&gt;&lt;\/b&gt; The aim of the current study was to determine operational long-term adherence to PAP and its predictors. &lt;b&gt;&lt;i&gt;Methods:&lt;\/i&gt;&lt;\/b&gt; In a retrospective single-center observational cohort study, we analyzed all patients referred to our center with suspected OSAS between November 2001 and November 2011. Baseline results and last follow-up data of each patient were analyzed. Kaplan-Meier estimates of adherence and Cox proportional hazard regression for age, gender, Epworth sleepiness scale (ESS) scores, body mass index, apnea-hypopnea index (AHI) and oxygen desaturation index (ODI) were performed. Evolution of adherence was analyzed in yearly cohorts comparing the proportion of patients discontinuing PAP within 6 and 12 months. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; Of 4,638 referrals, 2,187 confirmed OSAS patients started PAP, 297 (14%) were referred out to other centers to follow-up, 42 (2%) died, and 92 (5%) no longer needed PAP. Of 1,756 patients, the median follow-up was 36 months [95% confidence interval (CI) 33.6-37.8], and adherence at 1, 5 and 10 years was 74 (CI 71-75; n = 1,028), 55 (CI 53-58; n = 281) and 51% (CI 48-55; n = 10), respectively. Adherence is associated with ESS score [hazard ratio (HR) 0.60; CI 0.47-0.78], ODI (HR 0.50; CI 0.32-0.77) and AHI (HR 0.56; CI 0.37-0.85). In yearly cohorts according to inclusion date, the absconder rate at 6 and 12 months was 20 (CI 18-22) and 27% (CI 25-30) for the first 8 years and improved to 10 (CI 7-15) and 14% (CI 10-19) for the last 2 years, respectively. &lt;b&gt;&lt;i&gt;Conclusions:&lt;\/i&gt;&lt;\/b&gt; Long-term adherence to PAP in OSAS is associated with baseline measures of disease severity. After 2009, an improvement in the adherence rate was observed.<\/jats:p>","DOI":"10.1159\/000354186","type":"journal-article","created":{"date-parts":[[2013,11,5]],"date-time":"2013-11-05T08:44:01Z","timestamp":1383641041000},"page":"121-128","source":"Crossref","is-referenced-by-count":48,"title":["Baseline Predictors of Adherence to Positive Airway Pressure Therapy for Sleep Apnea: A 10-Year Single-Center Observational Cohort Study"],"prefix":"10.1159","volume":"87","author":[{"given":"Otto D.","family":"Schoch","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florent","family":"Baty","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jolanda","family":"Niedermann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jochen J.","family":"R\u00fcdiger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin H.","family":"Brutsche","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2013,11,5]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199304293281704"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.smrv.2010.10.002"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1103944"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200005113421901"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)71141-7"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(11)60589-8"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198210073071507"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD001106.pub2"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD007736"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1159\/000322838"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.159.4.9807111"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2010.135848"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1159\/000029408"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0022503"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1378\/chest.11-0709"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.163.3.2006168"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201106-0964OC"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201203-0448OC"}],"container-title":["Respiration"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/354186","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/354186","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T18:42:47Z","timestamp":1745433767000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000354186"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,11,5]]},"references-count":18,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2014,2,1]]},"published-print":{"date-parts":[[2014,2,6]]}},"URL":"https:\/\/doi.org\/10.1159\/000354186","archive":["Portico"],"relation":{},"ISSN":["0025-7931","1423-0356"],"issn-type":[{"value":"0025-7931","type":"print"},{"value":"1423-0356","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,11,5]]}}}