{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T04:35:24Z","timestamp":1745469324749,"version":"3.40.4"},"reference-count":15,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dermatology"],"published-print":{"date-parts":[[2013]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Background:&lt;\/i&gt;&lt;\/b&gt; Actinic keratosis (AK) is prevalent and has been widely studied in fair-skinned populations. However, this is not the case in eastern countries. AK in Asians has not been so thoroughly investigated. &lt;b&gt;&lt;i&gt;Objectives:&lt;\/i&gt;&lt;\/b&gt; To analyse the clinical and pathological features of a relatively large number of cases of AK diagnosed in older Chinese patients. &lt;b&gt;&lt;i&gt;Methods:&lt;\/i&gt;&lt;\/b&gt; Case histories of 328 patients with pathologically diagnosed AK were analysed retrospectively. Their demographic, clinical, pathological and treatment data were collected for analysis of associated factors. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; Lesions were usually distributed on the face, especially the cheeks and temples. The most frequent pathological type was hypertrophic. Only 34% of the cases had been diagnosed correctly as AK before biopsy; many were mistaken for seborrhoeic keratosis. &lt;b&gt;&lt;i&gt;Conclusions:&lt;\/i&gt;&lt;\/b&gt; Most patients were elderly females and there was a higher incidence of lesions on the face, and a lower incidence on the extremities and trunk; this finding contrasts with previous investigations in fair-skinned people.<\/jats:p>","DOI":"10.1159\/000354651","type":"journal-article","created":{"date-parts":[[2013,10,30]],"date-time":"2013-10-30T09:59:47Z","timestamp":1383127187000},"page":"316-320","source":"Crossref","is-referenced-by-count":2,"title":["Clinical and Pathological Study of 328 Cases of Actinic Keratosis in Eastern Chinese Patients"],"prefix":"10.1159","volume":"227","author":[{"given":"Yu-Mei","family":"Han","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lian-Jun","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xia","family":"Dou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qin-Ping","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2013,10,31]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.1998.02560.x"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1747.2000.00048.x"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2000.03541.x"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.1970.27"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197408)34:2<345::AID-CNCR2820340219>3.0.CO;2-0"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-0960.2007.00339.x"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.1996.535"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1994.tb08544.x"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440-0960.2002.00634.x"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2011.10337.x"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2007.33224.x"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1747.2000.00048.x"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-0960.1983.tb00256.x"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.141.4.507"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2006.07692.x"}],"container-title":["Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/354651","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/354651","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T18:48:14Z","timestamp":1745434094000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000354651"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013]]},"references-count":15,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2014,1,1]]},"published-print":{"date-parts":[[2014,1,7]]}},"URL":"https:\/\/doi.org\/10.1159\/000354651","archive":["Portico"],"relation":{},"ISSN":["1018-8665","1421-9832"],"issn-type":[{"type":"print","value":"1018-8665"},{"type":"electronic","value":"1421-9832"}],"subject":[],"published":{"date-parts":[[2013]]}}}