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Karger AG","issue":"2","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Caries Res"],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p>The study investigated the erosion\/abrasion-preventing potential of experimental NaF (1,400 ppm F&lt;sup&gt;-&lt;\/sup&gt;) and amine fluoride (AmF)\/NaF\/SnCl&lt;sub&gt;2&lt;\/sub&gt;\/chitosan (1,400 ppm F&lt;sup&gt;-&lt;\/sup&gt;, 3,500 ppm Sn&lt;sup&gt;2+&lt;\/sup&gt;, 0.5% chitosan) toothpastes relative to placebo and SnF&lt;sub&gt;2&lt;\/sub&gt; gel (970 ppm F&lt;sup&gt;-&lt;\/sup&gt;, 3,000 ppm Sn&lt;sup&gt;2+&lt;\/sup&gt;), and the impact of the demineralised dentine matrix on toothpaste effects. The study was a cyclic erosion\/intervention experiment (10 days). Samples were stored in mineral salt solution either without or with collagenase (from &lt;i&gt;Clostridium histolyticum&lt;\/i&gt; type VII; 100 U\/ml) for continuous removal of the organic matrix. To produce a comparable order of tissue loss, erosion was performed 6 \u00d7 30 s\/day with 0.5% citric acid in the latter and 6 \u00d7 90 s\/day with 1% citric acid in the former. Intervention was toothpaste slurry immersion (2 \u00d7 2 min\/day); half of the samples were additionally brushed for 15 s within this time (brushing machine, load 200 g). Tissue loss was determined profilometrically (mean \u00b1 SD; \u00b5m). Tissue loss values (without\/with brushing) for placebo, NaF, AmF\/NaF\/SnCl&lt;sub&gt;2&lt;\/sub&gt;\/chitosan and SnF&lt;sub&gt;2&lt;\/sub&gt; gel, respectively, were 11.6 \u00b1 3.1\/12.2 \u00b1 2.5, 12.7 \u00b1 3.1\/10.7 \u00b1 4.5, 8.7 \u00b1 2.1\/9.7 \u00b1 2.1 and 8.8 \u00b1 1.8\/&amp;#x200B;10.9 \u00b1 1.8 in the presence of the organic matrix and 10.7 \u00b1 3.2\/11.9 \u00b1 2.1, 8.2 \u00b1 4.0\/10.1 \u00b1 4.1, 8.7 \u00b1 2.9\/9.1 \u00b1 1.8 and 8.4 \u00b1 1.9\/7.5 \u00b1 1.5 in the absence of the organic matrix. Relative to placebo, the NaF formulation had no significant effects; the AmF\/NaF\/SnCl&lt;sub&gt;2&lt;\/sub&gt;\/chitosan formulation significantly reduced tissue loss between 20 and 25% except when applied without brushing in the absence of the organic matrix. The effects of the formulations were similar both in the presence and absence of the organic matrix. Sn&lt;sup&gt;2+&lt;\/sup&gt;\/F&lt;sup&gt;-&lt;\/sup&gt;-&amp;#x200B;containing formulations have the potential to reduce erosion\/abrasion even in the absence of demineralised collagen; seeking for more effective formulations is desirable.<\/jats:p>","DOI":"10.1159\/000354679","type":"journal-article","created":{"date-parts":[[2014,1,7]],"date-time":"2014-01-07T14:14:03Z","timestamp":1389104043000},"page":"163-169","source":"Crossref","is-referenced-by-count":54,"title":["Erosion\/Abrasion-Preventing Potential of NaF and F\/Sn\/Chitosan Toothpastes in Dentine and Impact of the Organic Matrix"],"prefix":"10.1159","volume":"48","author":[{"given":"C.","family":"Ganss","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Klimek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Schlueter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2014,1,3]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1875-595X.2003.tb00768.x"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bdj.4801418a"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0528.2002.300106.x"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-9969(01)00039-5"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1159\/000073922"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-263X.2011.01115.x"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1177\/00220345670460011201"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0722.2009.00617.x"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0722.2010.00742.x"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.archoralbio.2004.05.010"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1159\/000334318"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1159\/000252975"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1159\/000314671"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1177\/0022034510375291"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0722.2007.00466.x"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-008-0230-8"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2012.08.005"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1159\/000083159"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2009.06.006"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0722.2003.00074.x"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2007.01.003"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-051X.2003.00367.x"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1159\/000331391"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1159\/000261341"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1177\/088391159200700406"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1159\/000016587"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0528.1991.tb00169.x"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1159\/000325915"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1159\/000117807"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1046\/j.0909-8836.1999.eos1070301.x"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-5037.2004.00110.x"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2003.74.4.428"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bdj.4808695"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.2334\/josnusd.53.163"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.1080\/000163598423045"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.1016\/j.archoralbio.2010.02.003"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0722.2009.00647.x"},{"key":"ref38","doi-asserted-by":"publisher","DOI":"10.3109\/00016350903555395"},{"key":"ref39","doi-asserted-by":"publisher","DOI":"10.1177\/0022034511421928"},{"key":"ref40","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bdj.4805401"},{"key":"ref41","doi-asserted-by":"publisher","DOI":"10.1159\/000079629"},{"key":"ref42","doi-asserted-by":"publisher","DOI":"10.1159\/000057874"},{"key":"ref43","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2011.10.010"},{"key":"ref44","doi-asserted-by":"publisher","DOI":"10.1159\/000325946"},{"key":"ref45","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-0825.2005.01167.x"},{"key":"ref46","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.b.31844"},{"key":"ref47","doi-asserted-by":"publisher","DOI":"10.1177\/08959374970110042501"}],"container-title":["Caries 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