{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,29]],"date-time":"2025-11-29T07:49:39Z","timestamp":1764402579169,"version":"3.40.4"},"reference-count":14,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2013,9,4]],"date-time":"2013-09-04T00:00:00Z","timestamp":1378252800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"},{"start":{"date-parts":[[2013,9,4]],"date-time":"2013-09-04T00:00:00Z","timestamp":1378252800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Rep Neurol"],"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Background:&lt;\/i&gt;&lt;\/b&gt; Progressive multifocal leukoencephalopathy (PML) is a rapidly progressive, potentially fatal, demyelinating disease affecting immunosuppressed patients. PML is rarely reported in cases with no underlying disease or immunosuppression-associated condition. &lt;b&gt;&lt;i&gt;Case Report:&lt;\/i&gt;&lt;\/b&gt; We present a 72-year-old previously healthy woman who developed a progressive neurological condition affecting the entire nervous system which led to her death within 5 months. PML was diagnosed at autopsy. &lt;b&gt;&lt;i&gt;Conclusion:&lt;\/i&gt;&lt;\/b&gt; PML should be considered in patients with progressive neurological disorders involving the white matter, even in the absence of previous immunomodulatory treatment or immunosuppression.<\/jats:p>","DOI":"10.1159\/000354828","type":"journal-article","created":{"date-parts":[[2013,9,4]],"date-time":"2013-09-04T09:29:12Z","timestamp":1378286952000},"page":"149-154","source":"Crossref","is-referenced-by-count":15,"title":["Progressive Multifocal Leukoencephalopathy in an Immunocompetent Patient"],"prefix":"10.1159","volume":"5","author":[{"given":"Krisztina K.","family":"Johansen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sverre H.","family":"Torp","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jana","family":"Rydland","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan O.","family":"Aasly","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2013,9,4]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(71)91777-6"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiq097"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1002\/ana.20933"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2009.187666"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.20.5.479"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.111126"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1002\/ana.1004"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1086\/318120"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000160385.43633.34"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc1211805"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(10)70028-4"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01614-08"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1126\/science.1103492"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1086\/514617"}],"container-title":["Case Reports in Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/354828","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/354828","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T18:03:04Z","timestamp":1745431384000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000354828"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,9,4]]},"references-count":14,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2013,12,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000354828","archive":["Portico"],"relation":{},"ISSN":["1662-680X"],"issn-type":[{"type":"electronic","value":"1662-680X"}],"subject":[],"published":{"date-parts":[[2013,9,4]]}}}