{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T04:33:10Z","timestamp":1745469190613,"version":"3.40.4"},"reference-count":40,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2013,11,9]],"date-time":"2013-11-09T00:00:00Z","timestamp":1383955200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2013,11,9]],"date-time":"2013-11-09T00:00:00Z","timestamp":1383955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ophthalmologica"],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Purpose:&lt;\/i&gt;&lt;\/b&gt; To investigate the effects of polymorphisms of the age-related maculopathy susceptibility 2 &lt;i&gt;(ARMS2)&lt;\/i&gt; gene on the central visual field defects in retinitis pigmentosa (RP). &lt;b&gt;&lt;i&gt;Subjects and Methods:&lt;\/i&gt;&lt;\/b&gt; The visual field was evaluated using the 10-2 Swedish Interactive Threshold Algorithm Fast Program and mean deviation (MD) slope, and regression coefficients of average sensitivity of the central 4 points (Cent4) were compared between each genetic subgroup. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; The MD slope (right\/left) was as follows: GG, -1.37 \u00b1 2.18\/ -0.89 \u00b1 1.15; GT, -0.56 \u00b1 1.40\/-0.77 \u00b1 1.04; TT, -0.75 \u00b1 0.64\/ -0.38 \u00b1 0.92 dB\/year. The Cent4 was as follows: GG, -1.34 \u00b1 2.37\/-1.60 \u00b1 3.21; GT, -1.15 \u00b1 2.08\/1.07 \u00b1 1.80; TT, -1.20 \u00b1 0.91\/-0.65 \u00b1 1.37 dB\/year. No significant differences in the degree of progression were observed when comparing groups. &lt;b&gt;&lt;i&gt;Conclusions:&lt;\/i&gt;&lt;\/b&gt; These data suggest that polymorphisms of the &lt;i&gt;ARMS2&lt;\/i&gt; do not modify the progression of the central field of vision in RP patients.<\/jats:p>","DOI":"10.1159\/000355093","type":"journal-article","created":{"date-parts":[[2013,11,11]],"date-time":"2013-11-11T10:06:49Z","timestamp":1384164409000},"page":"51-57","source":"Crossref","is-referenced-by-count":0,"title":["Exclusion of Influences of ARMS2 Polymorphisms on the Central Visual Field in Retinitis 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