{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,8]],"date-time":"2025-11-08T12:11:20Z","timestamp":1762603880895,"version":"3.40.4"},"reference-count":6,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Caries Res"],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p>Today's fluoride-releasing varnishes (F-varnish) contain a wide variety of ingredients which present analytical challenges for measuring their total fluoride content. This study reports improved methods to measure fluoride content in F-varnishes. Six different commercially available F-varnishes that contain difluorosilane (0.1% F) or NaF (2.26% F) alone or in combination with calcium-phosphates were analyzed. In a vial, 1-3 drops (0.05-0.15 g) of varnish product was dispensed, dissolved in chloroform, equilibrated in TISAB and analyzed via fluoride ion-selective electrode. The average weight percentage of fluoride for all F-varnishes containing NaF ranged from 2.03 to 2.24% F, which is within 90% of the declared label concentration of 2.26% F. Analysis of the difluorosilane-containing product required an additional hydrolysis step. ANOVA found no significant difference between the 5% NaF varnishes at p &lt; 0.05. This method for fluoride analysis yields reliable and reproducible results and can be used for a wide variety of F-varnishes. The standard uncertainty for this method is \u00b14%. This method may become the basis for national and international standards that ensure the F-varnish products used in clinical practice have the fluoride content declared in the product literature.<\/jats:p>","DOI":"10.1159\/000355613","type":"journal-article","created":{"date-parts":[[2014,2,13]],"date-time":"2014-02-13T10:43:56Z","timestamp":1392288236000},"page":"306-311","source":"Crossref","is-referenced-by-count":3,"title":["Method for the Analysis of Total Fluoride in Fluoride-Releasing Dental Varnishes"],"prefix":"10.1159","volume":"48","author":[{"given":"C.M.","family":"Carey","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.S.","family":"Coleman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2014,2,14]]},"reference":[{"doi-asserted-by":"publisher","key":"ref1","DOI":"10.14219\/jada.archive.2006.0356"},{"doi-asserted-by":"publisher","key":"ref2","DOI":"10.1520\/D1179-10"},{"doi-asserted-by":"publisher","key":"ref3","DOI":"10.14219\/jada.archive.2000.0232"},{"doi-asserted-by":"publisher","key":"ref4","DOI":"10.1111\/j.1600-0528.2008.00427.x"},{"doi-asserted-by":"publisher","key":"ref5","DOI":"10.14219\/jada.archive.2002.0141"},{"doi-asserted-by":"publisher","key":"ref6","DOI":"10.1177\/154405910608500211"}],"container-title":["Caries Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/355613","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/355613","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T18:10:57Z","timestamp":1745431857000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000355613"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":6,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2014,7,1]]},"published-print":{"date-parts":[[2014,7,8]]}},"URL":"https:\/\/doi.org\/10.1159\/000355613","archive":["Portico"],"relation":{},"ISSN":["0008-6568","1421-976X"],"issn-type":[{"type":"print","value":"0008-6568"},{"type":"electronic","value":"1421-976X"}],"subject":[],"published":{"date-parts":[[2014]]}}}