{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T20:57:49Z","timestamp":1760043469043,"version":"3.40.4"},"reference-count":27,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2013,12,4]],"date-time":"2013-12-04T00:00:00Z","timestamp":1386115200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2013,12,4]],"date-time":"2013-12-04T00:00:00Z","timestamp":1386115200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dermatology"],"published-print":{"date-parts":[[2014]]},"abstract":"Pityriasis rosea (PR) is an acute, self-limiting exanthematous disease caused by the endogenous reactivation of human herpesvirus (HHV)-6 and\/or HHV-7 infection in conditions of altered immunity. In addition, many drugs have been incriminated as possible triggers of PR-like eruptions, characterized by clinical, morphological and histopathological features that differ from typical PR. Here, we report a case of PR in a patient with chronic hepatitis B, receiving pegylated interferon \u03b1<sub>2a<\/sub> (PEG-IFN-\u03b1<sub>2a<\/sub>). PR, arising after the second administration of the PEG-IFN-\u03b1<sub>2a<\/sub>, might be considered a clinical expression of the patient's altered immune condition as reported in the immune reconstitution inflammatory syndrome affecting patients with human immunodeficiency virus infection after high-dose antiretroviral therapy.<\/jats:p>","DOI":"10.1159\/000356176","type":"journal-article","created":{"date-parts":[[2013,12,4]],"date-time":"2013-12-04T08:31:35Z","timestamp":1386145895000},"page":"10-13","source":"Crossref","is-referenced-by-count":7,"title":["Pityriasis Rosea in a Hepatitis B-Positive Patient Treated with Pegylated Interferon \u03b1<sub>2a<\/sub>: Report of a Case and Review of the Literature"],"prefix":"10.1159","volume":"228","author":[{"given":"Francesco","family":"Drago","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanja","family":"Javor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linda","family":"Bruzzone","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesca","family":"Drago","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aurora","family":"Parodi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonino","family":"Picciotto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2013,12,4]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0022-202X.2005.23719.x"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)63203-5"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2008.07.045"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2013.01.033"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/S0001-7310(05)73051-9"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1179\/joc.2005.17.2.212"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1001\/archdermatol.2012.1968"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1053\/jhep.1996.v24.pm0008690394"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2210-10-15"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1111\/j.0736-8046.2004.21512.x"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1097\/MEG.0b013e32816e070b"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.3121\/cmr.2010.886"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1007\/s00105-006-1108-9"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/S0399-8320(06)73238-9"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2010.01088.x"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1747.2002.00200.x"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0560.2002.290606.x"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2006.01721.x"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1097\/COH.0b013e32833ed774"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200806-858OC"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0b013e31829f6df2"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2010-05-285080"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1097\/QCO.0b013e328352b664"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1016\/j.clim.2010.02.010"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1001\/2013.jamadermatol.503"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1159\/000070931"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jit252"}],"container-title":["Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/356176","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/356176","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T18:16:04Z","timestamp":1745432164000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000356176"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,12,4]]},"references-count":27,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2014,2,1]]},"published-print":{"date-parts":[[2014,2,6]]}},"URL":"https:\/\/doi.org\/10.1159\/000356176","archive":["Portico"],"relation":{},"ISSN":["1018-8665","1421-9832"],"issn-type":[{"type":"print","value":"1018-8665"},{"type":"electronic","value":"1421-9832"}],"subject":[],"published":{"date-parts":[[2013,12,4]]}}}