{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T12:26:46Z","timestamp":1763036806968,"version":"3.40.4"},"reference-count":11,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2013,12,17]],"date-time":"2013-12-17T00:00:00Z","timestamp":1387238400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2013,12,17]],"date-time":"2013-12-17T00:00:00Z","timestamp":1387238400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dermatology"],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p>The rosette structure is a dermoscopic sign visible under polarized light, characterized by 4 white points arranged as a 4-leaf clover. It has been mainly described in facial sun-damaged skin and actinic keratosis, although it has also been found in squamous and basal cell carcinomas, and in 2 cases of hypomelanotic melanomas. We describe 2 different cases of pigmented incipient melanomas with the presence of multiple rosettes and shiny white structures on dermoscopy. In the reflectance confocal microscope they exhibit a disarranged epidermal architecture with atypical and dendritic cells. Histological examination showed focal hyperkeratosis and a normal corneal layer presented alternatively. To our knowledge this is the first description of rosette structures in pigmented melanomas. Based on a proper dermoscopic- confocal-histopathological correlation, we hypothesize that rosettes could correspond to optic phenomena due to changes in the superficial epidermal reaction and in the acrosyringia.<\/jats:p>","DOI":"10.1159\/000356822","type":"journal-article","created":{"date-parts":[[2013,12,17]],"date-time":"2013-12-17T07:40:06Z","timestamp":1387266006000},"page":"31-33","source":"Crossref","is-referenced-by-count":20,"title":["Dermoscopic Rosettes as a Clue for Pigmented Incipient Melanoma"],"prefix":"10.1159","volume":"228","author":[{"given":"Tatiana","family":"Gonz\u00e1lez-\u00c1lvarez","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miquel","family":"Armengot-Carb\u00f3","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alicia","family":"Barreiro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ivette","family":"Alarc\u00f3n","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristina","family":"Carrera","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adriana","family":"Garc\u00eda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Josep","family":"Malvehy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susana","family":"Puig","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2013,12,17]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(02)00679-4"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.137.10.1343"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.143.3.329"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-0960.2010.00672.x"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1001\/archdermatol.2009.28"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1001\/archdermatol.2011.2114"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2011.04317.x"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1001\/archdermatol.2011.618"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1001\/archdermatol.2009.86"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1001\/archdermatol.2011.312"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/S0738-081X(02)00220-1"}],"container-title":["Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/356822","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/356822","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T18:22:24Z","timestamp":1745432544000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000356822"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,12,17]]},"references-count":11,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2014,2,1]]},"published-print":{"date-parts":[[2014,2,6]]}},"URL":"https:\/\/doi.org\/10.1159\/000356822","archive":["Portico"],"relation":{},"ISSN":["1018-8665","1421-9832"],"issn-type":[{"type":"print","value":"1018-8665"},{"type":"electronic","value":"1421-9832"}],"subject":[],"published":{"date-parts":[[2013,12,17]]}}}