{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T04:34:00Z","timestamp":1745469240763,"version":"3.40.4"},"reference-count":11,"publisher":"S. Karger AG","issue":"12","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Onkologie"],"published-print":{"date-parts":[[2013]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Background: &lt;\/i&gt;&lt;\/b&gt;Treatment of germ cell tumours with cisplatin-based chemotherapy results in cure for the majority of patients. There is, however, a small but significant mortality rate, reported to be higher in patients with multiple co-morbidities. &lt;b&gt;&lt;i&gt;Case Report: &lt;\/i&gt;&lt;\/b&gt;We report our management of a renal transplant patient with spina bifida, who was diagnosed with stage IIIC, poor-risk, non-seminomatous germ cell carcinoma. A marker-negative partial response, which has been maintained more than 2 years following completion of treatment, was seen following chemotherapy with cisplatin and etoposide. Performance status has been preserved at pre-treatment levels. &lt;b&gt;&lt;i&gt;Conclusion: &lt;\/i&gt;&lt;\/b&gt;Administration of cisplatin-based chemotherapy is feasible for treatment of renal transplant patients with advanced non-seminomatous germ cell tumours. Treatment strategies require careful planning and monitoring. Dose modifications may be required. This case highlights a favourable outcome in spite of multiple obstacles to ideal management.<\/jats:p>","DOI":"10.1159\/000356837","type":"journal-article","created":{"date-parts":[[2013,11,22]],"date-time":"2013-11-22T08:15:15Z","timestamp":1385108115000},"page":"760-762","source":"Crossref","is-referenced-by-count":1,"title":["Metastatic Germ Cell Tumour Following Renal Transplantation"],"prefix":"10.1159","volume":"36","author":[{"given":"Donna M.","family":"Graham","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William D.","family":"Plant","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nick J.","family":"Mayer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Derek G.","family":"Power","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2013,11,20]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6600272"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdq262"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdg020"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1093\/jjco\/28.9.546"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8223(94)92540-2"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1186\/cc2872"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/92.3.205"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1111\/j.1349-7006.2010.01676.x"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.3109\/02841869609084013"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1159\/000338481"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-4295(96)00104-5"}],"container-title":["Onkologie"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/356837","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/356837","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T18:22:34Z","timestamp":1745432554000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000356837"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013]]},"references-count":11,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2013,12,1]]},"published-print":{"date-parts":[[2013,12,11]]}},"URL":"https:\/\/doi.org\/10.1159\/000356837","archive":["Portico"],"relation":{},"ISSN":["0378-584X","1423-0240"],"issn-type":[{"type":"print","value":"0378-584X"},{"type":"electronic","value":"1423-0240"}],"subject":[],"published":{"date-parts":[[2013]]}}}