{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T17:31:44Z","timestamp":1770485504384,"version":"3.49.0"},"reference-count":28,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dermatology"],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Background:&lt;\/i&gt;&lt;\/b&gt; &lt;i&gt;Fusarium&lt;\/i&gt; onychomycoses are weakly responsive or unresponsive to standard onychomycosis treatments with oral terbinafine and itraconazole. &lt;b&gt;&lt;i&gt;Objective:&lt;\/i&gt;&lt;\/b&gt; To examine whether the use of terbinafine and itraconazole, which are highly effective in fighting &lt;i&gt;Trichophyton&lt;\/i&gt; onychomycoses, could be a cause of the high incidence of &lt;i&gt;Fusarium&lt;\/i&gt; nail infections. &lt;b&gt;&lt;i&gt;Methods:&lt;\/i&gt;&lt;\/b&gt; Polymerase chain reaction methods were used to detect both &lt;i&gt;Fusarium&lt;\/i&gt; spp. and &lt;i&gt;Trichophyton&lt;\/i&gt; spp. in nails of patients who had either received treatment previously or not. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; No significant microbiological differences were found between treated and untreated patients. In 24 of 79 cases (30%), &lt;i&gt;Fusarium&lt;\/i&gt; spp. was detected in samples of patients having had no previous antifungal therapy and when &lt;i&gt;Trichophyton&lt;\/i&gt; spp. grew in culture. &lt;b&gt;&lt;i&gt;Conclusion:&lt;\/i&gt;&lt;\/b&gt; Oral terbinafine and itraconazole treatments do not appear to favor the establishment of &lt;i&gt;Fusarium&lt;\/i&gt; spp. in onychomycosis.<\/jats:p>","DOI":"10.1159\/000357764","type":"journal-article","created":{"date-parts":[[2014,2,28]],"date-time":"2014-02-28T07:52:41Z","timestamp":1393573961000},"page":"225-232","source":"Crossref","is-referenced-by-count":14,"title":["Oral Terbinafine and Itraconazole Treatments against Dermatophytes Appear Not to Favor the Establishment of &lt;b&gt;&lt;i&gt;Fusarium&lt;\/i&gt;&lt;\/b&gt; spp. in Nail"],"prefix":"10.1159","volume":"228","author":[{"given":"Julie","family":"Verrier","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olympia","family":"Bontems","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Florence","family":"Baudraz-Rosselet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michel","family":"Monod","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2014,2,28]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2011.02.038"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0507.1989.tb02192.x"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1111\/j.1610-0387.2006.05877.x"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1111\/myc.12016"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.7547\/87507315-91-9-456"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.46723-0"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2009.09291.x"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.05164-11"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2007.03120.x"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0507.2008.01619.x"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(00)90129-4"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1111\/j.1470-9465.2004.00845.x"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1159\/000277762"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/14.5.1167"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1080\/13693780410001712043"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1159\/000248356"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00869-05"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.00259-12"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1038\/nature08850"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1080\/09603120701254862"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.3109\/13693780903451828"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1080\/13693780410001661482"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.49.7.2840-2844.2005"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01600-05"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1976.tb05171.x"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1159\/000335093"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.41.2.826-830.2003"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.12015"}],"container-title":["Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/357764","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/357764","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T18:31:15Z","timestamp":1745433075000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000357764"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":28,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2014,6,1]]},"published-print":{"date-parts":[[2014,6,10]]}},"URL":"https:\/\/doi.org\/10.1159\/000357764","archive":["Portico"],"relation":{},"ISSN":["1018-8665","1421-9832"],"issn-type":[{"value":"1018-8665","type":"print"},{"value":"1421-9832","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014]]}}}