{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T18:17:14Z","timestamp":1785176234190,"version":"3.55.0"},"reference-count":31,"publisher":"S. Karger AG","issue":"3-4","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur Neurol"],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Background:&lt;\/i&gt;&lt;\/b&gt; Oculopalatal tremor (OPT) is a delayed complication of a brainstem lesion, characterized by involuntary contractions of the soft palate associated with a synchronized ocular pendular nystagmus. MRI reveals inferior olivary nucleus hypersignal\/hypertrophy (IONH). Our objective was to refine the clinical profile of patients with OPT and to report a few oddities in both presentation and evolution. &lt;b&gt;&lt;i&gt;Methods:&lt;\/i&gt;&lt;\/b&gt; We performed a retrospective study of patients diagnosed with OPT and a literature search. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; From our database, we retrieved 5 men and 3 women with a diagnosis of OPT. Eighty-two patients with OPT were retrieved from the literature and were compiled with our series. The average age was 54 years and there was a male predominance. Brainstem vascular lesion was the most common etiology (80%). Prominent vertical pendular nystagmus was found in 90%. Dissociated nystagmus was mostly associated to unilateral contralateral IONH on MRI, while bilateral symmetrical nystagmus was due to a bilateral IONH in the majority of cases. Three oddities were found amongst our 8 patients: prominent nystagmus ipsilateral to IONH; disappearance of IONH on MRI despite persisting nystagmus, and asymptomatic OPT. &lt;b&gt;&lt;i&gt;Conclusion:&lt;\/i&gt;&lt;\/b&gt; The clinical profile of OPT is rather stereotyped. Rarely do patients deviate from the classical description of OPT.<\/jats:p>","DOI":"10.1159\/000360531","type":"journal-article","created":{"date-parts":[[2014,8,18]],"date-time":"2014-08-18T07:04:50Z","timestamp":1408345490000},"page":"144-149","source":"Crossref","is-referenced-by-count":13,"title":["Oculopalatal Tremor: Variations on a Theme by Guillain and Mollaret"],"prefix":"10.1159","volume":"72","author":[{"given":"Liuna","family":"Jang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7ois-Xavier","family":"Borruat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2014,8,16]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000258665.37827.f6"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1097\/WCO.0b013e32835c60e6"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(01)78357-2"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/109.3.431"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e31827debc3"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.86.1.116"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.45.5.431"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.35.1.36"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410170123"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.36.1.86"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1097\/00041327-199503000-00028"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/118.2.369"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(96)30743-4"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1038\/eye.1997.4"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1038\/eye.1997.79"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1097\/00041327-200106000-00003"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/S0039-6257(02)00283-7"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000095962.45509.B2"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2007.01997.x"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1016\/j.parkreldis.2008.01.020"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000318287.29513.6d"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000327614.16569.08"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e318219fa9c"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e318238eeac"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.3109\/01658107.2011.609606"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2011.222570"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2008.03.016"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1002995107"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awp323"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1002\/ana.21991"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2011.06118.x"}],"container-title":["European Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/360531","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/360531","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T17:30:50Z","timestamp":1745429450000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000360531"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":31,"journal-issue":{"issue":"3-4","published-online":{"date-parts":[[2014,10,1]]},"published-print":{"date-parts":[[2014,10,9]]}},"URL":"https:\/\/doi.org\/10.1159\/000360531","archive":["Portico"],"relation":{"is-supplemented-by":[{"id-type":"doi","id":"10.6084\/m9.figshare.5126323","asserted-by":"subject"}]},"ISSN":["0014-3022","1421-9913"],"issn-type":[{"value":"0014-3022","type":"print"},{"value":"1421-9913","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014]]}}}