{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T23:38:46Z","timestamp":1782603526805,"version":"3.54.5"},"reference-count":6,"publisher":"S. Karger AG","issue":"6","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ORL"],"published-print":{"date-parts":[[2014]]},"abstract":"<b><i>Objective:<\/i><\/b> To investigate changes in the upper airway and its surrounding soft tissue and to characterize the extent and severity of upper airway obstruction in 136 obstructive sleep apnea\/hypopnea syndrome (OSAHS) patients who were awake. <b><i>Methods:<\/i><\/b> OSAHS patients and healthy controls were evaluated by fiber-optic nasolaryngoscopy and MRI. The cross-sectional area and pharyngeal wall thickness of the retropalatal, retroglossal and epiglottic region were determined. <b><i>Results:<\/i><\/b> Ninety-five percent of the mild OSAHS subjects had single-plane obstruction (vs. severe OSAHS, p < 0.05), 5.0% of the mild OSAHS subjects had two-plane obstruction (p < 0.05) and none of them had three-plane obstruction (p < 0.05). The cross-sectional area of the retropalatal, retroglossal and epiglottic region progressively declined as the severity of OSAHS increased (severe OSAHS vs. controls, p < 0.05). The lateral pharyngeal wall was significantly thicker in OSAHS subjects than in healthy controls (p < 0.05). The cross-sectional area of the soft palate in moderate and severe OSAHS subjects was markedly larger than that of the healthy controls (p < 0.05) and positively correlated with the apnea\/hypopnea index (p < 0.05). <b><i>Conclusion: <\/i><\/b>Moderate and severe OSAHS patients exhibit multi-plane obstruction of the upper airway, particularly in the retropalatal and retroglossal region. The severity of OSAHS negatively correlates with the thickness, length and cross-sectional area size of the soft palate.<\/jats:p>","DOI":"10.1159\/000362245","type":"journal-article","created":{"date-parts":[[2014,12,22]],"date-time":"2014-12-22T07:20:20Z","timestamp":1419232820000},"page":"321-328","source":"Crossref","is-referenced-by-count":5,"title":["Characterization of Upper Airway Obstruction by Fiber-Optic Nasolaryngoscopy and MRI in Preoperative OSAHS Patients"],"prefix":"10.1159","volume":"76","author":[{"given":"Song","family":"Shi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanghui","family":"Xia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minhui","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaixuan","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fei","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donghui","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shicai","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongliang","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2014,12,20]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm\/137.4.895"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198512000-00009"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.152.5.7582313"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1097\/MLG.0b013e31816422ea"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.152.5.7582313"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1067\/mhn.2002.126477"}],"container-title":["ORL"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/362245","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/362245","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T17:37:11Z","timestamp":1745429831000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000362245"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":6,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2015,2,1]]},"published-print":{"date-parts":[[2015,2,5]]}},"URL":"https:\/\/doi.org\/10.1159\/000362245","archive":["Portico"],"relation":{},"ISSN":["0301-1569","1423-0275"],"issn-type":[{"value":"0301-1569","type":"print"},{"value":"1423-0275","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014]]}}}