{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:51:44Z","timestamp":1787017904699,"version":"build-2736575974"},"reference-count":15,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2014,12,2]],"date-time":"2014-12-02T00:00:00Z","timestamp":1417478400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2014,12,2]],"date-time":"2014-12-02T00:00:00Z","timestamp":1417478400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Haematol"],"published-print":{"date-parts":[[2015]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Backgrounds\/Aims:&lt;\/i&gt;&lt;\/b&gt; Relationships of mean platelet volume (MPV) and thrombopoietin (TPO) with platelet turnover assessed by glycocalicin measurement were evaluated in thrombocytopenic patients. &lt;b&gt;&lt;i&gt;Methods:&lt;\/i&gt;&lt;\/b&gt; MPV, glycocalicin and platelet-associated IgG (PA-IgG) were measured in 107 patients with idiopathic thrombocytopenic purpura (ITP) and 19 patients with hypoproductive thrombocytopenia (HPT; aplastic anemia or leukemia), and TPO was measured in 53 ITP and 12 HPT patients. All the included ITP patients had PA-IgG \u2265300% and glycocalicin \u226550% of control values, and HPT patients had PA-IgG &lt;300% and glycocalicin &lt;50% of control values. &lt;b&gt;&lt;i&gt;Results and Conclusions: &lt;\/i&gt;&lt;\/b&gt;MPV was higher in ITP than in HPT patients: 9.56 \u00b1 1.69 and 7.59 \u00b1 0.90 fl (p &lt; 0.001). In the ITP group a direct correlation was detected between MPV and glycocalicin (r = 0.344, p &lt; 0.001). This interaction was essentially expressed in patients with normal\/increased glycocalicin (\u2265100% of control; r = 0.470, p &lt; 0.001, n = 64). TPO was greatly enhanced in HPT in comparison with ITP patients (958 \u00b1 659 and 11 \u00b1 27 pg\/ml, p &lt; 0.001). In the ITP group a reverse correlation was detected between TPO and glycocalicin (r = -0.373, p = 0.006). \u00a9 2014 S. Karger AG, Basel<\/jats:p>","DOI":"10.1159\/000362531","type":"journal-article","created":{"date-parts":[[2014,12,2]],"date-time":"2014-12-02T02:35:04Z","timestamp":1417487704000},"page":"295-299","source":"Crossref","is-referenced-by-count":13,"title":["Relationships of Mean Platelet Volume and Plasma Thrombopoietin with Glycocalicin Levels in Thrombocytopenic Patients"],"prefix":"10.1159","volume":"133","author":[{"given":"Svetlana G.","family":"Khaspekova","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olga N.","family":"Shustova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nina V.","family":"Golubeva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergey A.","family":"Vasiliev","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexey V.","family":"Mazurov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2014,12,2]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.2450\/2008.0012-08"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-387837-3.00040-7"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.2830300404"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1097\/00043426-199805000-00003"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198710223171701"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1309\/RAW2-0LQW-8YTX-941V"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2257.2005.00726.x"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2004.05357.x"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1179\/102453309X426182"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0609.1996.tb00492.x"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0609.1992.tb00913.x"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1021\/bi00402a021"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/0049-3848(91)90371-3"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1097\/00001721-199709000-00004"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-553X.2007.00885.x"}],"container-title":["Acta Haematologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/362531","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/362531","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/362531","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T13:39:54Z","timestamp":1745415594000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000362531"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,12,2]]},"references-count":15,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2015,4,1]]},"published-print":{"date-parts":[[2015,4,9]]}},"URL":"https:\/\/doi.org\/10.1159\/000362531","archive":["Portico"],"relation":{},"ISSN":["0001-5792","1421-9662"],"issn-type":[{"value":"0001-5792","type":"print"},{"value":"1421-9662","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,12,2]]}}}