{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T08:33:50Z","timestamp":1789893230997,"version":"4.0.1"},"reference-count":33,"publisher":"S. Karger AG","issue":"2","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dermatology"],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Background:&lt;\/i&gt;&lt;\/b&gt; Recently, a consensus Bullous Pemphigoid Disease Area Index (BPDAI) was proposed to measure therapeutic outcomes in bullous pemphigoid (BP). &lt;b&gt;&lt;i&gt;Objective:&lt;\/i&gt;&lt;\/b&gt; To compare BPDAI with other clinical parameters of disease activity at baseline and to describe the variations of BPDAI during the initial phase of treatment. &lt;b&gt;&lt;i&gt;Methods:&lt;\/i&gt;&lt;\/b&gt; Thirty BP patients were included and followed for 1 year. BPDAI was assessed at baseline and on days 30, 90 and 360 by the same investigator. Concomitantly, the number of daily new blisters, the skin surface area of erythematous\/eczematous\/urticarial plaques and blisters\/erosions, total lesion area (TLA), pruritus score and mucosal involvement were recorded. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; At baseline, BPDAI was 46.7 \u00b1 25 (mean \u00b1 SD); it was well correlated with erythematous\/eczematous\/urticarial skin surface (r = 0.63), TLA (r = 0.83), number of daily new blisters (r = 0.7; p \u2264 0.0002) and anti-BP180 autoantibodies (r = 0.49; p = 0.006), but not with anti-BP230 autoantibodies. For the 8 patients with severe BP at baseline, the mean BPDAI was 76.5, versus 35.9 for moderate BP (p = 0.0007). A value of 56 was proposed as a cut-off value for severe BP. BPDAI decreased to 11.9 \u00b1 8.7, 10.7 \u00b1 12.7 and 2.5 \u00b1 4.1 on days 30, 90 and 360, respectively. &lt;b&gt;&lt;i&gt;Conclusion:&lt;\/i&gt;&lt;\/b&gt; BPDAI rapidly decreased during the early treatment stage of BP with variations almost totally conditioned by the skin activity component.<\/jats:p>","DOI":"10.1159\/000362717","type":"journal-article","created":{"date-parts":[[2014,10,27]],"date-time":"2014-10-27T03:56:30Z","timestamp":1414382190000},"page":"116-122","source":"Crossref","is-referenced-by-count":32,"title":["Assessment of Bullous Pemphigoid Disease Area Index during Treatment: A Prospective Study of 30 Patients"],"prefix":"10.1159","volume":"229","author":[{"given":"C\u00e9lia","family":"L\u00e9vy-Sitbon","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Coralie","family":"Barbe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie","family":"Plee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne-Laure","family":"Goeldel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Antonicelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziad","family":"Reguia\u00ef","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Damien","family":"Jolly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florent","family":"Grange","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Bernard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2014,7,5]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1995.01690130050009"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2012.35"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.annder.2011.01.009"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.annder.2011.01.004"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.yadr.2007.07.013"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD002292"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2010.301"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1159\/000106574"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1996.03890270044006"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1001\/archdermatol.2011.23"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2008.01.012"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2009.72"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.clindermatol.2011.03.017"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2011.06.032"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/854795"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.134.9.1075"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa011592"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2008.412"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1093\/geronj\/46.4.M139"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3956(75)90026-6"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1016\/S0923-1811(02)00109-3"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1016\/j.clim.2008.04.012"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2008.07.022"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.176.3.2015"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2006.07601.x"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdermsci.2004.10.007"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1159\/000337545"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2013.5757"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.136.2.174"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.5021\/ad.2012.24.1.45"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.136.6.763"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.1999.02617.x"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1993.tb00150.x"}],"container-title":["Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/362717","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/362717","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T13:41:54Z","timestamp":1745415714000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000362717"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":33,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2014,10,1]]},"published-print":{"date-parts":[[2014,10,30]]}},"URL":"https:\/\/doi.org\/10.1159\/000362717","archive":["Portico"],"relation":{},"ISSN":["1018-8665","1421-9832"],"issn-type":[{"value":"1018-8665","type":"print"},{"value":"1421-9832","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014]]}}}