{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T23:30:27Z","timestamp":1770334227010,"version":"3.49.0"},"reference-count":18,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Respiration"],"published-print":{"date-parts":[[2014]]},"abstract":"<b><i>Background:<\/i><\/b> Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is an increasingly used mediastinal sampling technique. Many centres use conscious sedation in an ambulatory setting to optimise the flow of patients, save costs and shorten recovery time. The only EBUS-TBNA patient satisfaction study published so far used deep conscious sedation with propofol. To our knowledge, ours is the largest prospective study evaluating the experience of patients undergoing EBUS-TBNA using light conscious sedation without propofol. <b><i>Objectives:<\/i><\/b> To evaluate the patient tolerability of EBUS-TBNA under mild conscious sedation. <b><i>Methods:<\/i><\/b> Eighty-two<b> <\/b>consecutive patients between January 2011 and November 2011 requiring EBUS-TBNA under light conscious sedation for either mediastinal staging of lung cancer or the diagnosis of suspected mediastinal disease due to malignancy or granulomatous disease were invited to complete a questionnaire after the intervention. The collection of data included the diagnostic yield, the number and size of nodes sampled and the dose of sedative medication administered. <b><i>Results:<\/i><\/b> The average dose of sedative agents administered was 59.4 \u03bcg fentanyl and 3.2 mg midazolam. The sensitivity of EBUS-TBNA for the cancer staging, cancer diagnosis and granulomatous disease cohorts was 90.0, 94.1 and 87.5%, respectively. The most commonly reported symptom was a cough in 65 (93%) patients. Of these patients, 46 (71%) described the severity as being mild. All but 9 patients (61\/70 or 87%) stated that they would definitely or probably undergo a repeat EBUS-TBNA. <b><i>Conclusions:<\/i><\/b> This single-centre UK study confirms that EBUS-TBNA under light conscious sedation is a well-tolerated procedure maintaining the expected diagnostic performance, with patients reporting a high degree of satisfaction with both the test and the information received beforehand.<\/jats:p>","DOI":"10.1159\/000363063","type":"journal-article","created":{"date-parts":[[2014,9,9]],"date-time":"2014-09-09T07:51:41Z","timestamp":1410249101000},"page":"244-250","source":"Crossref","is-referenced-by-count":21,"title":["Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration: Patient Satisfaction under Light Conscious Sedation"],"prefix":"10.1159","volume":"88","author":[{"given":"Abiramy","family":"Jeyabalan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew R.L.","family":"Medford","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2014,8,21]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1159\/000356921"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1159\/000346574"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1097\/00000421-198212000-00014"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1097\/MCP.0b013e32832b8a45"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.3816\/CLC.2004.s.017"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1159\/000277931"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.12968\/hmed.2011.72.6.312"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200203-231OC"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1067\/mem.2000.104195"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-200204000-00031"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1093\/qjmed\/hcp136"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1159\/000346987"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.2174\/1574887111308010009"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1046\/j.1525-1497.1999.00293.x"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1378\/chest.12-0317"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1159\/000350428"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1159\/000323520"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1843.1998.tb00101.x"}],"container-title":["Respiration"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/363063","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/363063","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T17:45:23Z","timestamp":1745430323000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000363063"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":18,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2014,9,1]]},"published-print":{"date-parts":[[2014,9,15]]}},"URL":"https:\/\/doi.org\/10.1159\/000363063","archive":["Portico"],"relation":{},"ISSN":["0025-7931","1423-0356"],"issn-type":[{"value":"0025-7931","type":"print"},{"value":"1423-0356","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014]]}}}