{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T18:31:40Z","timestamp":1769193100020,"version":"3.49.0"},"reference-count":18,"publisher":"S. Karger AG","issue":"2","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neonatology"],"published-print":{"date-parts":[[2014]]},"abstract":"<b><i>Background:<\/i><\/b> Gases for respiratory support at birth are typically \u2018cold and dry', which may increase the risk of hypothermia and lung injury. <b><i>Objectives:<\/i><\/b> To determine the feasibility of using heated humidification from birth. <b><i>Method:<\/i><\/b> A humidifier targeting 37\u00b0C, a manual-fill chamber and a Neopuff Infant T-piece resuscitator and circuit were attached to a face mask and a manikin. Recordings using 20 ml H<sub>2<\/sub>O for humidification and a flow of 10 l\/min were undertaken. Temperature and relative humidity (RH) were recorded. Additional recordings were made, each with one alteration to baseline (50 ml H<sub>2<\/sub>O for humidification, auto-fill chamber, a flow of 8 l\/min, addition of circuit extension piece, warmed humidification H<sub>2<\/sub>O, increased ambient temperature and targeting 31\u00b0C). The duration of heated humidification and the response to disconnecting the power were investigated. <b><i>Results:<\/i><\/b> The baseline circuit achieved 95% RH and 31\u00b0C in 3 min, >99% RH in 7 min and \u226535\u00b0C in 9 min. No circuit alterations resulted in faster gas conditioning. The extended length circuit and targeting 31\u00b0C reduced the maximum temperature achieved. A flow of 8 l\/min resulted in slower heating and humidification. The baseline circuit delivered heated humidification for 39 min. Without power, the temperature and humidity fell below international standards in 3 min. <b><i>Conclusion:<\/i><\/b> Rapid gas conditioning for newborn stabilisation is feasible using the experimental set-up, \u226520 ml H<sub>2<\/sub>O and a flow of 10 l\/min. The circuit could be used immediately once switched on. Without power, conditioning is quickly lost. Investigation of the clinical effects of gas conditioning is warranted.<\/jats:p>","DOI":"10.1159\/000363126","type":"journal-article","created":{"date-parts":[[2014,6,27]],"date-time":"2014-06-27T07:01:19Z","timestamp":1403852479000},"page":"156-162","source":"Crossref","is-referenced-by-count":5,"title":["Feasibility and Practical Considerations for Heating and Humidifying Gases during Newborn Stabilisation: An in vitro Model"],"prefix":"10.1159","volume":"106","author":[{"given":"Louise S.","family":"Owen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer A.","family":"Dawson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robin","family":"Middleburgh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephanie","family":"Buttner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lorraine","family":"McGrory","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter G.","family":"Davis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2014,6,27]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2010.08.002"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2010-2972B"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1111\/jpc.12393"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD004210.pub4"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.clp.2006.12.009"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1007\/BF03025671"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2011.08.027"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2013.04.004"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-199611000-00025"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/45.8.844"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-009-1624-z"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(89)80567-0"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-200202000-00015"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1378\/chest.117.1.142"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1378\/chest.116.2.403"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/45.4.363"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2006-0943"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2009-2656"}],"container-title":["Neonatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/363126","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/363126","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T17:45:46Z","timestamp":1745430346000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000363126"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":18,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2014,8,1]]},"published-print":{"date-parts":[[2014,8,7]]}},"URL":"https:\/\/doi.org\/10.1159\/000363126","archive":["Portico"],"relation":{},"ISSN":["1661-7800","1661-7819"],"issn-type":[{"value":"1661-7800","type":"print"},{"value":"1661-7819","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014]]}}}