{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T22:22:44Z","timestamp":1791238964102,"version":"4.1.0"},"reference-count":10,"publisher":"S. Karger AG","issue":"5-6","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur Neurol"],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Background\/Methods:&lt;\/i&gt;&lt;\/b&gt; To find out the prevalence of aquaporin-antibody (Aqp-Ab) and characterize Aqp-Ab associated clinical features in NMO, Aqp-1 and Aqp-4-Abs were examined using radioimmunoprecipitation and cell-based assays, respectively. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; Aqp-4 and Aqp-1-Abs were detected in 20\/30 and 8\/30 NMO patients, respectively. One patient was Aqp-1-Ab single-positive, 13 patients were Aqp-4-Ab single-positive, 7 patients were Aqp-4\/Aqp-1-Ab double-positive and 9 patients were seronegative. All double-positive patients had optic neuritis during the first attack. Only 2\/29 MS patients and none of the control idiopathic intracranial hypertension patients were Aqp-1-Ab positive. &lt;b&gt;&lt;i&gt;Conclusion:&lt;\/i&gt;&lt;\/b&gt; Aqp-1-Ab is usually detected in Aqp-4-Ab positive NMO patients and might be involved in optic neuritis pathogenesis.<\/jats:p>","DOI":"10.1159\/000364904","type":"journal-article","created":{"date-parts":[[2014,9,29]],"date-time":"2014-09-29T06:59:30Z","timestamp":1411973970000},"page":"271-272","source":"Crossref","is-referenced-by-count":14,"title":["Aquaporin-1 Antibody in Neuromyelitis Optica Patients"],"prefix":"10.1159","volume":"72","author":[{"given":"Erdem","family":"T\u00fcz\u00fcn","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Tzartos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esme","family":"Ekizo\u011flu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christos","family":"Stergiou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paraskevi","family":"Zisimopoulou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arzu","family":"\u00c7oban","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erking\u00fcl","family":"Shugaiv","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Recai","family":"T\u00fcrko\u011flu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Murat","family":"K\u00fcrt\u00fcnc\u00fc","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bet\u00fcl","family":"Baykan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Socrates","family":"Tzartos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2014,9,27]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000216139.44259.74"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e31822c61b1"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-010-5780-4"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0074773"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.mam.2012.03.008"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1789.2007.00774.x"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-013-1116-7"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1002\/ana.22366"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1177\/0333102411434167"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-010-5499-2"}],"container-title":["European Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/364904","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/364904","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/364904","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T17:52:55Z","timestamp":1745430775000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000364904"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":10,"journal-issue":{"issue":"5-6","published-online":{"date-parts":[[2014,11,1]]},"published-print":{"date-parts":[[2014,11,28]]}},"URL":"https:\/\/doi.org\/10.1159\/000364904","archive":["Portico"],"relation":{},"ISSN":["0014-3022","1421-9913"],"issn-type":[{"value":"0014-3022","type":"print"},{"value":"1421-9913","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014]]}}}