{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,4]],"date-time":"2026-03-04T21:39:42Z","timestamp":1772660382680,"version":"3.50.1"},"reference-count":25,"publisher":"S. Karger AG","issue":"2","license":[{"start":{"date-parts":[[2014,7,2]],"date-time":"2014-07-02T00:00:00Z","timestamp":1404259200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"},{"start":{"date-parts":[[2014,7,2]],"date-time":"2014-07-02T00:00:00Z","timestamp":1404259200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Rep Oncol"],"abstract":"<jats:p>A 61-year-old male, who had been admitted to another hospital due to disseminated intravascular coagulation (DIC), was referred to our hospital. Total colonoscopy, abdominal dynamic CT and positron-emission tomography revealed bone metastasis and multiple lymphocytic metastases from transverse colon cancer in addition to disseminated carcinomatosis of the bone marrow (DCBM). We immediately performed chemotherapy with XELOX + bevacizumab and denosumab against DCBM from transverse colon cancer in order to avoid radical surgery. In addition, we initiated the administration of recombinant human soluble thrombomodulin for 1 week to treat DIC. The patient was able to tolerate and receive 4 cycles of chemotherapy without any severe side effects. After receiving the 4 cycles of treatment, he recovered from DIC, and the bone and multiple lymphocytic metastases disappeared.<\/jats:p>","DOI":"10.1159\/000365001","type":"journal-article","created":{"date-parts":[[2014,7,3]],"date-time":"2014-07-03T08:18:57Z","timestamp":1404375537000},"page":"426-434","source":"Crossref","is-referenced-by-count":15,"title":["A Report of Disseminated Carcinomatosis of the Bone Marrow Originating from Transverse Colon Cancer Successfully Treated with Chemotherapy Using XELOX plus Bevacizumab"],"prefix":"10.1159","volume":"7","author":[{"given":"Masayasu","family":"Naito","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6583-7352","authenticated-orcid":false,"given":"Yoichiro","family":"Yoshida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naoya","family":"Aisu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shu","family":"Tanimura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seiichiro","family":"Hoshino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshihiro","family":"Tanaka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoshi","family":"Nimura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuo","family":"Tamura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuichi","family":"Yamashita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2014,7,2]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.31.1056"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.3919\/jjsa.61.1256"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.11280\/gee1973b.44.1949"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.5833\/jjgs.35.431"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.3919\/jjsa.63.964"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.3919\/jjsa.64.2238"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.5035\/nishiseisai.54.77"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.3919\/jjsa.66.124"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.5833\/jjgs.39.265"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.3919\/jjsa.68.136"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.3919\/jjsa.68.394"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.3919\/jjsa.68.943"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.3862\/jcoloproctology.62.65"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.11405\/nisshoshi.107.1151"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.3919\/jjsa.72.444"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.11405\/nisshoshi.108.1244"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1186\/cc10228"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1007\/BF02603417"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1007\/BF02554846"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1016\/S1072-7515(03)00136-4"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.135.5.530"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.5060"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1159\/000328805"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1159\/000339614"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7819-11-39"}],"container-title":["Case Reports in Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/365001","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/365001","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T17:53:52Z","timestamp":1745430832000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000365001"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,7,2]]},"references-count":25,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2014,8,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000365001","archive":["Portico"],"relation":{},"ISSN":["1662-6575"],"issn-type":[{"value":"1662-6575","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,7,2]]}}}