{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T10:14:27Z","timestamp":1770977667182,"version":"3.50.1"},"reference-count":19,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gynecol Obstet Invest"],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Background:&lt;\/i&gt;&lt;\/b&gt; To evaluate the feasibility of conization without a prior punch biopsy for patients with abnormal cytology. &lt;b&gt;&lt;i&gt;Methods:&lt;\/i&gt;&lt;\/b&gt; A retrospective review was performed for 700 patients who underwent conization at a single institution from January 2003 to August 2012. Each of these patients was assigned to one of two groups, either the \u2018see-and-treat' group or the \u2018three-step' group, depending on whether the patient had undergone a punch biopsy before conization or not. The final histologic results of two groups were compared. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; The overtreatment risk was higher in the \u2018see-and-treat' group in patients with atypical squamous cells of undetermined significance\/low-grade squamous intraepithelial lesion (ASCUS\/LSIL) cytology (64.7% in the \u2018see-and-treat' group vs. 36.5% in the \u2018three-step' group; p = 0.001). There was no significant statistical difference in the rate of cervical dysplasia or invasive carcinoma in patients with high-grade squamous intraepithelial lesion (HSIL) cytology between groups (91.8% in the \u2018see-and-treat' group vs. 93.5% in the \u2018three-step' group; p = 0.793). &lt;b&gt;&lt;i&gt;Conclusion:&lt;\/i&gt;&lt;\/b&gt; The patients with HSIL on cytology can be managed by a \u2018see-and-treat' strategy with a low risk of overtreatment. On the other hand, the \u2018three-step' management is more appropriate in patients with ASCUS\/LSIL cytology.<\/jats:p>","DOI":"10.1159\/000365476","type":"journal-article","created":{"date-parts":[[2014,10,21]],"date-time":"2014-10-21T08:14:36Z","timestamp":1413879276000},"page":"239-243","source":"Crossref","is-referenced-by-count":4,"title":["The Overtreatment Risk of See-and-Treat Strategy in Management of Abnormal Cervical Cytology"],"prefix":"10.1159","volume":"78","author":[{"given":"Ji Ye","family":"Kim","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Doo Haeng","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun Hyeok","family":"Kang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kye Hyun","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyo Won","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Woo Young","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2014,10,21]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2006.07.022"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1126\/science.95.2469.438"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2009.07.027"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(11)90622-X"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1159\/000329324"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2009.04.011"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1080\/11038120701208158"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(06)68181-6"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1001\/jama.291.17.2100"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2012.02.017"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1001\/jama.287.16.2114"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1159\/000345864"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2011.01.021"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2003.457"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/93.4.293"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(02)01922-1"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.20599"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.b2548"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2003.282"}],"container-title":["Gynecologic and Obstetric Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/365476","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/365476","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/365476","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T17:59:16Z","timestamp":1745431156000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000365476"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":19,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2014,11,1]]},"published-print":{"date-parts":[[2014,11,27]]}},"URL":"https:\/\/doi.org\/10.1159\/000365476","archive":["Portico"],"relation":{},"ISSN":["0378-7346","1423-002X"],"issn-type":[{"value":"0378-7346","type":"print"},{"value":"1423-002X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014]]}}}