{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,18]],"date-time":"2026-07-18T08:53:50Z","timestamp":1784364830697,"version":"3.55.0"},"reference-count":30,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Fetal Diagn Ther"],"published-print":{"date-parts":[[2015]]},"abstract":"<b><i>Introduction:<\/i><\/b> Twin-twin transfusion syndrome (TTTS) and twin anemia-polycythemia sequence (TAPS) are classified as distinct clinical disorders associated with unbalanced blood flow through placental vascular communications. Typically, TAPS placentas demonstrate few <1 mm arteriovenous (AV) communications, and at fetoscopy the twins are visibly pale and plethoric. <b><i>Materials and Methods:<\/i><\/b> In a cohort of TTTS patients who underwent laser surgery, those with preoperative findings suggestive of anemia\/polycythemia (AP) were compared to those with TTTS alone. AP was defined as middle cerebral artery peak systolic velocity in one twin >1.5 multiples of the median (MoM), and <1.0 MoM in the other. <b><i>Results:<\/i><\/b> Of 369 TTTS patients, 9 (2.4%) met criteria for preoperative AP. The mean number (\u00b1SD) of AV communications in the TTTS + AP group was 5.6 \u00b1 5.7, compared with 8.8 \u00b1 4.8 in the TTTS-alone group (p = 0.013). Five TTTS + AP patients (56%) had a few thin AV communications (mean 2.8 \u00b1 1.6); all 5 had visibly pale and plethoric twins. The remaining 4 (44%) had large or numerous anastomoses (mean 10.5 \u00b1 6.8); none had fetal skin color discordance. <b><i>Discussion:<\/i><\/b> Preoperative AP affected 2% of TTTS patients. Of these, approximately half had placental and skin color findings typically reported with isolated TAPS.<\/jats:p>","DOI":"10.1159\/000365919","type":"journal-article","created":{"date-parts":[[2015,2,16]],"date-time":"2015-02-16T10:59:18Z","timestamp":1424084358000},"page":"274-280","source":"Crossref","is-referenced-by-count":26,"title":["Pre-Operative Twin Anemia\/Polycythemia in the Setting of Twin-Twin Transfusion Syndrome (TTTS)"],"prefix":"10.1159","volume":"37","author":[{"given":"Kristi R.","family":"Van Winden","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruben A.","family":"Quintero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eftichia V.","family":"Kontopoulos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa M.","family":"Korst","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arlyn","family":"Llanes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramen H.","family":"Chmait","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2015,2,14]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1097\/00003081-199003000-00006"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1097\/00001703-200304000-00013"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.siny.2008.02.002"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2007.05.009"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jp.7200292"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1159\/000304512"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2012.01.009"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e318187e1ff"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1002\/uog.7508"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1002\/pd.4177"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2006.01.010"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1080\/14767050701591827"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.3109\/14767050903128618"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1159\/000263622"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0223(199809)18:9<941::AID-PD427>3.0.CO;2-G"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1002\/pd.2491"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2008.03.050"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(89)90521-8"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1002\/pd.1175"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1159\/000213065"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1002\/pd.4191"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2005.08.069"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2009.07.046"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2010.02.032"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2005.08.062"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2010.04.006"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2009.01.010"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2004.12.018"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1002\/uog.12492"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2014.05.012"}],"container-title":["Fetal Diagnosis and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/365919","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/365919","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T17:33:34Z","timestamp":1745429614000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000365919"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015]]},"references-count":30,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2015,5,1]]},"published-print":{"date-parts":[[2015,5,19]]}},"URL":"https:\/\/doi.org\/10.1159\/000365919","archive":["Portico"],"relation":{},"ISSN":["1015-3837","1421-9964"],"issn-type":[{"value":"1015-3837","type":"print"},{"value":"1421-9964","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015]]}}}