{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T04:31:11Z","timestamp":1745469071643,"version":"3.40.4"},"reference-count":15,"publisher":"S. Karger AG","issue":"2","license":[{"start":{"date-parts":[[2014,11,12]],"date-time":"2014-11-12T00:00:00Z","timestamp":1415750400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2014,11,12]],"date-time":"2014-11-12T00:00:00Z","timestamp":1415750400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Fetal Diagn Ther"],"published-print":{"date-parts":[[2015]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Objective:&lt;\/i&gt;&lt;\/b&gt; The aim of this retrospective study was to assess the fetal biparietal diameter (BPD) and head circumference (HC) in the second trimester of pregnancy in fetuses with open spinal dysraphism. &lt;b&gt;&lt;i&gt;Methods:&lt;\/i&gt;&lt;\/b&gt; BPD and HC were measured at 16-26 weeks in 74 fetuses with open spinal dysraphism and compared with reference values. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; BPD was smaller in fetuses with open spinal dysraphism. Of all cases with open spinal dysraphism, 62.2% had a BPD &lt;3rd percentile and 79.7% had a BPD &lt;10th percentile. Of all patients, 54.1% had an HC &lt;3rd percentile and 74.3% had an HC &lt;10th percentile. &lt;b&gt;&lt;i&gt;Conclusion:&lt;\/i&gt;&lt;\/b&gt; Almost all fetuses with open neural tube defects have a smaller BPD and HC at 16-26 weeks compared with reference values, which implicates that this is part of the phenotype of children with open spinal dysraphism instead of an independent prognostic marker for a poor cognitive outcome.<\/jats:p>","DOI":"10.1159\/000366157","type":"journal-article","created":{"date-parts":[[2014,11,12]],"date-time":"2014-11-12T10:20:35Z","timestamp":1415787635000},"page":"135-140","source":"Crossref","is-referenced-by-count":5,"title":["Small Biparietal Diameter and Head Circumference Are Part of the Phenotype instead of Independent Prognostic Markers in Fetuses with Spinal Dysraphism"],"prefix":"10.1159","volume":"37","author":[{"given":"Inge","family":"Cuppen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dagmar","family":"de Bruijn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Niels","family":"Geerdink","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan J.","family":"Rotteveel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mich\u00e8l A.A.P.","family":"Willemsen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John M.G.","family":"van Vugt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jaco W.","family":"Pasman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nel","family":"Roeleveld","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2014,11,12]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.reprotox.2005.03.009"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8749.2009.03543.x"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1017\/S0012162204000684"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(86)91610-7"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2012.05.014"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1002\/uog.162"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1002\/uog.5225"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1002\/uog.4026"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1980.tb04522.x"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1007\/s00381-003-0792-3"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.siny.2013.09.004"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.earlhumdev.2013.09.010"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.1997.10020094.x"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8749.2003.tb00896.x"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2005.075887"}],"container-title":["Fetal Diagnosis and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/366157","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/366157","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T17:35:55Z","timestamp":1745429755000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000366157"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,11,12]]},"references-count":15,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2015,2,1]]},"published-print":{"date-parts":[[2015,3,5]]}},"URL":"https:\/\/doi.org\/10.1159\/000366157","archive":["Portico"],"relation":{},"ISSN":["1015-3837","1421-9964"],"issn-type":[{"type":"print","value":"1015-3837"},{"type":"electronic","value":"1421-9964"}],"subject":[],"published":{"date-parts":[[2014,11,12]]}}}