{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T00:44:50Z","timestamp":1780447490089,"version":"3.54.1"},"reference-count":27,"publisher":"S. Karger AG","issue":"2","license":[{"start":{"date-parts":[[2014,11,27]],"date-time":"2014-11-27T00:00:00Z","timestamp":1417046400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2014,11,27]],"date-time":"2014-11-27T00:00:00Z","timestamp":1417046400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dermatology"],"published-print":{"date-parts":[[2015]]},"abstract":"<jats:p>Acrodermatitis continua of Hallopeau (ACH) is a rare form of chronic acral pustular eruption. Considered to be a variant of pustular psoriasis, it is a refractory condition that may not respond to conventional treatments. We report herein the case of a 53-year-old patient whose ACH was refractory to all conventional systemic treatment modalities and to anti-tumour necrosis factor. Because he had increased plasma levels of interleukin (IL)-1\u03b2, he received anakinra for 7 weeks, without further improvement however. Achievement of complete response was obtained with ustekinumab 90 mg s.c. every 12 weeks combined with acitretin; the plasma level of IL-1\u03b2 concomitantly returned to normal. This case report is associated with a review on recent data on ACH treatment with biological agents, including anakinra and ustekinumab.<\/jats:p>","DOI":"10.1159\/000367690","type":"journal-article","created":{"date-parts":[[2014,12,1]],"date-time":"2014-12-01T07:42:26Z","timestamp":1417419746000},"page":"97-100","source":"Crossref","is-referenced-by-count":22,"title":["Acrodermatitis Continua of Hallopeau Treated Successfully with Ustekinumab and Acitretin after Failure of Tumour Necrosis Factor Blockade and Anakinra"],"prefix":"10.1159","volume":"230","author":[{"given":"Jordane","family":"Saunier","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00e9bastien","family":"Debarbieux","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denis","family":"Jullien","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorna","family":"Garnier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"St\u00e9phane","family":"Dalle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1995-2434","authenticated-orcid":false,"given":"Luc","family":"Thomas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2014,11,27]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2011.04993.x"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1159\/000277415"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.3109\/09546634.2013.848259"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-1540"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.crohns.2011.08.017"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2010.09.667"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1001\/archdermatol.2011.2473"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.det.2013.04.001"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2012-3935"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-153-1-201007060-00030"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.12548"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2013.361"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2012.490"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1159\/000346572"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.12805"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2013.230"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.13012"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1007\/s00403-013-1327-8"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1165\/ajrcmb.23.4.3959"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2567.2011.03522.x"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2013.10.043"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1007\/s00403-012-1229-1"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2010.09995.x"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1159\/000346243"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.12150"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.12272"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1016\/j.adengl.2013.01.001"}],"container-title":["Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/367690","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/367690","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T17:41:53Z","timestamp":1745430113000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000367690"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,11,27]]},"references-count":27,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2015,2,1]]},"published-print":{"date-parts":[[2015,2,26]]}},"URL":"https:\/\/doi.org\/10.1159\/000367690","archive":["Portico"],"relation":{},"ISSN":["1018-8665","1421-9832"],"issn-type":[{"value":"1018-8665","type":"print"},{"value":"1421-9832","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,11,27]]}}}