{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T12:52:12Z","timestamp":1778935932596,"version":"3.51.4"},"reference-count":16,"publisher":"S. Karger AG","issue":"5","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Cytologica"],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Introduction:&lt;\/i&gt;&lt;\/b&gt; We previously identified a high level of accuracy among our cytotechnologists (CTs) for identifying nuclear atypia in thyroid fine-needle aspiration (FNA) specimens. Herewith, we present our CT performance at screening for microfollicular atypia. &lt;b&gt;&lt;i&gt;Methods:&lt;\/i&gt;&lt;\/b&gt; 8,814 thyroid FNA specimens were identified in our archives, all screened by 1 of 11 CTs and signed out by a cytopathologist. A subsample of cases was categorized either as atypia of uncertain significance (AUS) with microfollicular proliferation (AUS-F) or suspicious for a follicular neoplasm (SFN). &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; The agreement rate was low between CTs and cytopathologists for SFN and AUS-F. Only 55.8% of SFN screening diagnoses were upheld; 27.9% were downgraded to AUS, 10.4% were downgraded to benign, and 5% were upgraded. Of AUS-F screening diagnoses, 35.5% were upheld, 33.7% were downgraded to benign, and 20.2% were upgraded to SFN. Among all cases, two-step discrepancies were uncommon. &lt;b&gt;&lt;i&gt;Conclusion:&lt;\/i&gt;&lt;\/b&gt; Most disagreements were one-category discrepancies between AUS-F and SFN. The evaluation of microfollicular atypia is challenging given that certain follicular lesions cannot be definitively diagnosed on cytology, a high level of subjectivity is involved in the interpretation of such lesions, and the presence of nuclear or Hurthle cell atypia may complicate the diagnosis.<\/jats:p>","DOI":"10.1159\/000367882","type":"journal-article","created":{"date-parts":[[2014,12,3]],"date-time":"2014-12-03T07:21:30Z","timestamp":1417591290000},"page":"432-438","source":"Crossref","is-referenced-by-count":5,"title":["Cytotechnologist Performance for Screening Microfollicular Atypia in Indeterminate Thyroid Fine-Needle Aspirates"],"prefix":"10.1159","volume":"58","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8822-5655","authenticated-orcid":false,"given":"Christopher J.","family":"VandenBussche","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew T.","family":"Olson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christina","family":"Adams","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Syed Z.","family":"Ali","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2014,10,17]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1159\/000338646"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1159\/000354079"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1309\/AJCP84AXSRABZCTZ"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.4132\/KoreanJPathol.2013.47.5.405"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jasc.2014.02.003"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1309\/GANX5UDM9BU3B9CK"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1309\/BHGR-GPH0-UMBM-49VQ"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.5858\/arpa.2012-0120-CC"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1309\/AJCPPHLWMI3JV4LA"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2012-3898"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.22423"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1159\/000333232"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1159\/000351664"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.2307\/2331554"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-014-3508-x"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1159\/000362681"}],"container-title":["Acta Cytologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/367882","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/367882","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T17:44:05Z","timestamp":1745430245000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000367882"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":16,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2014,10,1]]},"published-print":{"date-parts":[[2014,12,4]]}},"URL":"https:\/\/doi.org\/10.1159\/000367882","archive":["Portico"],"relation":{},"ISSN":["0001-5547","1938-2650"],"issn-type":[{"value":"0001-5547","type":"print"},{"value":"1938-2650","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014]]}}}