{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T05:20:32Z","timestamp":1783488032618,"version":"3.55.0"},"reference-count":40,"publisher":"Bioscientifica","issue":"4","license":[{"start":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T00:00:00Z","timestamp":1771200000000},"content-version":"vor","delay-in-days":4142,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":["journals.bioscientifica.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2014,12,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Background: Agranulocytosis is a serious side effect of antithyroid drugs. Objective: To ascertain the knowledge of patients and review the quality of information available on the internet. Methods: A questionnaire survey was performed for patients receiving antithyroid drugs. Patients attending endocrine clinics who were receiving antithyroid drug treatment (group A, n = 33) were interviewed. A further national cohort of patients (group B, n = 100) treated with antithyroid drugs, participated in an online survey. Results: 60.9% of responders were not aware of the common symptoms of agranulocytosis. 18.6% had never received any information about side effects. Of the 108 patients who recalled receiving information, 30% rated the quality as \u2018poor' or \u2018not good at all'. Structured interviews of group A patients revealed that almost half (45.5%, 15\/33) had experienced symptoms that could be indicative of agranulocytosis, but only 53.3% (8\/15) had a blood count checked. A review of 20 selected patient information internet sites revealed a significant variation in advice given to patients. Conclusions: Inadequate knowledge about agranulocytosis among patients receiving antithyroid drug treatment is common. The available information on the internet is variable and inconsistent.<\/jats:p>","DOI":"10.1159\/000367990","type":"journal-article","created":{"date-parts":[[2014,10,15]],"date-time":"2014-10-15T02:59:53Z","timestamp":1413341993000},"page":"245-251","update-policy":"https:\/\/doi.org\/10.1530\/crossmarkpolicy-17","source":"Crossref","is-referenced-by-count":20,"title":["Patient Knowledge of Antithyroid Drug-Induced Agranulocytosis"],"prefix":"10.1530","volume":"3","author":[{"given":"Jonah","family":"Robinson","sequence":"first","affiliation":[{"name":"1Department of Endocrinology, Royal Victoria Infirmary, Newcastle upon Tyne, Harrogate, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Max","family":"Richardson","sequence":"additional","affiliation":[{"name":"1Department of Endocrinology, Royal Victoria Infirmary, Newcastle upon Tyne, Harrogate, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janis","family":"Hickey","sequence":"additional","affiliation":[{"name":"2British Thyroid Foundation, Harrogate, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andy","family":"James","sequence":"additional","affiliation":[{"name":"1Department of Endocrinology, Royal Victoria Infirmary, Newcastle upon Tyne, Harrogate, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon H.","family":"Pearce","sequence":"additional","affiliation":[{"name":"1Department of Endocrinology, Royal Victoria Infirmary, Newcastle upon Tyne, Harrogate, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steve G.","family":"Ball","sequence":"additional","affiliation":[{"name":"1Department of Endocrinology, Royal Victoria Infirmary, Newcastle upon Tyne, Harrogate, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Quinton","sequence":"additional","affiliation":[{"name":"1Department of Endocrinology, Royal Victoria Infirmary, Newcastle upon Tyne, Harrogate, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margaret","family":"Morris","sequence":"additional","affiliation":[{"name":"1Department of Endocrinology, Royal Victoria Infirmary, Newcastle upon Tyne, Harrogate, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margaret","family":"Miller","sequence":"additional","affiliation":[{"name":"1Department of Endocrinology, Royal Victoria Infirmary, Newcastle upon Tyne, Harrogate, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7320-5574","authenticated-orcid":false,"given":"Petros","family":"Perros","sequence":"additional","affiliation":[{"name":"1Department of Endocrinology, Royal Victoria Infirmary, Newcastle upon Tyne, Harrogate, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"416","published-online":{"date-parts":[[2014,10,15]]},"reference":[{"key":"2026070712450604900_ref1","doi-asserted-by":"crossref","unstructured":"Golden SH, Robinson KA, Saldanha I, et al: Clinical review: prevalence and incidence of endocrine and metabolic disorders in the United States: a comprehensive review. 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